The use of plasmapheresis and intravenous laser blood irradiation in treatment of patients with newly diagnosed tuberculosis at the late stages of hiv infection (references review)

Polyakov, Alex; Поляков, А А; Kornilova, Z. H.; Kornilova, Z. Kh.; Demikhova, Olga V.

doi:10.23888/pavlovj20174655-668

Cited by 2 publications

(3 citation statements)

References 7 publications

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“…We found reports of human studies using ILIB to treat pneumonia, bronchitis, asthma, and tuberculosis. However, the majority of these articles was in Russian, restricting our analysis to their abstracts [ 11 , 12 , 21 – 24 , 27 ]. Unfortunatelly, the details of the PBM parameters (mainly involving lasers) were not mentioned in the abstract, which hindered the discussion, as well as limiting the future application of this technology.…”

Section: Resultsmentioning

confidence: 99%

“…ILIB treatment increased the therapeutic effect and stimulated the resolution of the disease, and made it possible to stabilize the course of tuberculosis with less pronounced changes in the lungs. Similarly, Polyakov et al [ 27 ] showed that ILIB applied to patients with tuberculosis in the early stages of chemotherapy led to an increased effectiveness of treatment, contributing to the cessation of bacterial excretion in the sputum and reduction of the hospitalization period. Stimulation of the immune system could be attributed to the effects of ILIB in the blood microcirculation, inducing vasodilation, analgesic effects, improving the oxygen transport in the blood, and normalizing some metabolic processes related to proteins, lipids, carbohydrates, and intracellular energy balance.…”

Section: Resultsmentioning

confidence: 99%

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Intravascular laser irradiation of blood (ILIB) used to treat lung diseases: a short critical review

et al. 2023

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Intravascular laser irradiation of blood (ILIB) was developed to treat cardiovascular diseases due to its rheological effects. In its original form, ILIB was applied by an intravenous optical fiber, restricting its application. However, this technique was modified to non-invasive irradiation through the radial artery, now called vascular photobiomodulation (VPBM). Many studies have used both, ILIB and VPBM, to treat lung diseases. It is well established that lung diseases affect more than 300 million people worldwide with high morbidity and mortality rates. In this short critical review, we discuss the potential benefits of photobiomodulation to treat lung diseases using these two approaches. The search was performed in the electronic database of MEDLINE (Medical Literature Analysis and Retrieval System Online) via PubMed. The data search was carried out from 1991 to 2017. We selected a total of 10 clinical studies using either ILIB or VPBM, in addition to 2 experimental studies in animals. The respiratory diseases treated in these studies included bronchitis, asthma, pneumonia, and tuberculosis. The results showed overall beneficial effects on lung diseases, characterized by a reduction in the inflammatory cascade and antioxidant effects, improvement of hemodynamic parameters, the efficiency of gas exchange, and reduction of hospitalization periods. In conclusion, all studies showed promising effects of ILIB in both animal and human studies. The studies did not discuss any disadvantages or contraindications. However, further studies are needed in order to understand the dosimetry, and the literature is lacking in randomized, controlled clinical trials. Thus, this review highlights the need for additional studies using this approach.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Intravascular laser irradiation of blood (ILIB) used to treat lung diseases: a short critical review

et al. 2023

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“…Таким образом, проведенное исследование подтвердило данные отечественных и зарубежных авторов [4][5][6][7], показывающие, что при операциях по поводу распространенного туберкулеза бронхоплевральные осложнения отмечаются в три раза чаще, чем при неспецифических заболеваниях легких. Это обусловлено казеозными изменениями во внутригрудных лимфатических узлах, что диктует целесообразность выполнения селективной лимфаденэктомии.…”

Section: результаты и их обсуждениеunclassified

Effectiveness of mediastinal lymphadenectomy in surgical treatment of generalized destructive pulmonary tuberculosis

Papkov

Витальевич²,

Гиллер

et al. 2018

I.P. Pavlov Russian Medical Biological Herald

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Bronchopleural complications after pneumonectomy in generalized destructive tuberculosis are associated with the presence of intrathoracic lymph nodes (ITLN) with caseous alterations. Aim. To improve the effectiveness of surgical treatment of patients with generalized destructive pulmonary tuberculosis by development and introduction of the method of mediastinal lymphadenectomy in tuberculous lesion of mediastinal lymph nodes. Materials and Methods. Results of surgical treatment of 515 patients with generalized destructive pulmonary tuberculosis were analyzed. In 274 of them the surgical treatment was supplemented with mediastinal lymphadenectomy (the main group). In the control group (241 patients) only resection was performed without removing lymph nodes. Results. Analysis of the postoperative course of the disease in both groups of patients (with mediastinal lymphadenectomy and without it) showed that bronchopleural complications occurred in 7 (2.6%) cases in the main group and in 30 (12.4%, p<0.05) cases in the control group. In the main group exacerbation of the specific process was noted in 1 patient (0.4%), and in comparison group in 9 patients (3.7%, p<0.05). Elimination of macroscopically altered ITLN in widespread destructive tuberculosis permitted to reduce the complications rate in the postoperative period by 64.8% (p<0.05). Indications to removal of IHLN included: a) enlargement of ITLN (>2 sm) and in duration; b) fusion with the surrounding tissues, softening of the node tissue in its caseous melting, c) existence of yellowish or whiter in comparison with the surrounding tissue inclusions in the node being manifestations of tuberculous granuloma. In histological, cytological and bacteriological examination, these macroscopic signs in 97% of cases indicated active tuberculosis of mediastinal lymph nodes. Conclusions. In 97% of cases, widespread destructive secondary pulmonary tuberculosis runs with an active specific process in mediastinal lymph nodes which makes it reasonable to perform a selective lymphadenectomy in such group of patients. Secondary damage of different groups of intrathoracic lymph nodes by the active process depended on localization of lung destructions and occurred along the routes of lymph drainage from them. Reliable signs of active tuberculous of ITLN include: more than 2.0 cm lymph node enlargement, in duration, periadenitis, fluctuation and in homogeneity. Removal of macroscopically altered intra-thoracic lymph nodes in widespread destructive pulmonary tuberculosis permits to reduce the rate of complications in the postoperative period by 64.8%.

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The use of plasmapheresis and intravenous laser blood irradiation in treatment of patients with newly diagnosed tuberculosis at the late stages of hiv infection (references review)

Cited by 2 publications

References 7 publications

Intravascular laser irradiation of blood (ILIB) used to treat lung diseases: a short critical review

Intravascular laser irradiation of blood (ILIB) used to treat lung diseases: a short critical review

Effectiveness of mediastinal lymphadenectomy in surgical treatment of generalized destructive pulmonary tuberculosis

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