2015
DOI: 10.1213/ane.0000000000000442
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The Use of Pulse Pressure Variation and Stroke Volume Variation in Spontaneously Breathing Patients to Assess Dynamic Arterial Elastance and to Predict Arterial Pressure Response to Fluid Administration

Abstract: Introduction We aimed to audit the prescribing practice on a busy 14-bedd general ICU, and develop standardised practices and tools to improve safety. Prescribing errors occur as commonly as in 10% of UK hospital admissions, costing 8.5 extra bed days per admission, and costing the National Health Service an estimated £1 billion per annum [1]. The majority of these mistakes are avoidable [2]. Methods We audited the daily infusion charts of all patients in three separate spot checks, over 1 week. We assessed al… Show more

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Cited by 67 publications
(40 citation statements)
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“…This finding is in agreement with previous reports in which steady assessment of arterial load-as measured by Ea, C and SVRfailed to predict the blood pressure response to fluid loading [34][35][36]. This finding is in agreement with previous reports in which steady assessment of arterial load-as measured by Ea, C and SVRfailed to predict the blood pressure response to fluid loading [34][35][36].…”
Section: Discussionsupporting
confidence: 92%
“…This finding is in agreement with previous reports in which steady assessment of arterial load-as measured by Ea, C and SVRfailed to predict the blood pressure response to fluid loading [34][35][36]. This finding is in agreement with previous reports in which steady assessment of arterial load-as measured by Ea, C and SVRfailed to predict the blood pressure response to fluid loading [34][35][36].…”
Section: Discussionsupporting
confidence: 92%
“…Similar results were reported in the FENICE study concerning indications for fluid challenge . As noted by the authors, this seems paradoxical since fluids are usually administered to increase tissue perfusion, and many clinical markers cannot adequately predict microcirculatory impairment . In a qualitative comparison to Oldner et al.…”
Section: Discussionsupporting
confidence: 77%
“…Minimally invasive monitors such as the Vigileo/ FloTrac system, and oesophageal Doppler combined with minimally invasive arterial pressure monitor can be used to estimate PPV/SVV in mechanically ventilated patients [108,110], while noninvasive monitoring (model flow based devices - Figure 3) can also be used in patients with spontaneous breathing [111]. Important is the fact that SVR should be normal to achieve correct data of SVV.…”
Section: Assessment Of Afterloadmentioning
confidence: 99%
“…Echocardiography is able to rapidly identify the cause of hypotension, and it remains the mainstay diagnostic tool to assess cardiac pathology and haemodynamics. Both TOE and TTE can provide qualitative and quantitative information about cardiac systolic and diastolic function, structure and function of valves, absence of myocardial ischaemia, and intra-cardiac structures [3,110].…”
Section: Assessment Of Cardiac Contractilitymentioning
confidence: 99%