The seismic assessment of reinforced concrete (RC) structures is commonly carried out neglecting previous damage, eventually induced by other phenomena, although different forms of hazard can affect a structure during its existence. The coexistence of many hazard sources is very common, i.e., in countries affected by landslides, also characterized by high seismicity, like Italy. The aim of this work is both to demonstrate the potential utility of satellite data derived from the Differential Synthetic Aperture Radar Interferometry (DInSAR) to support the structural health monitoring of a RC infilled building within a landslide-affected area and to assess its safety conditions after experiencing two different hazards, that are landslide and earthquake. A 3D model of the case study building, including also infills, is created based on the information available from a geometrical survey, obtaining the missing parameters from literature. The seismic assessment of the building structural elements, caused by the design seismic action, is initially shown. Then, the seismic assessment is repeated, considering the building to be in a state of known landslide-induced stress-strain condition. Finally, an interesting comparison is proposed between the safety condition of the building expected in both cases, with or without the consideration of the precedent landslide-induced displacements.