The use of silicone gel in the treatment of fresh surgical scars: a randomized study

Giorgi, Vincenzo De; Sestini, Serena; Mannone, Francesca; Papi, Federica; Alfaioli, Barbara; Gori, Alessia; Lotti, Torello

doi:10.1111/j.1365-2230.2008.03096.x

Cited by 44 publications

(44 citation statements)

References 11 publications

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“…79 Other measures, such as wearing a supportive bra or body corset, can additionally reduce the risk of KD located in the upper trunk or the midsternal region. The use of silicone as a prophylactic tool has been studied extensively 28,[80][81][82][83] and, with the exception of a study by Niessen et al, 83 the results so far have been favourable. 84 Topical steroid tape has also been shown to be effective in preventing recurrence, but has the potential for poor compliance as it is reliant on its continued application by the patient.…”

Section: Surgical Excision and Adjuvant Therapymentioning

confidence: 99%

Strategic management of keloid disease in ethnic skin: a structured approach supported by the emerging literature

Uddin

Bayat

2013

Br J Dermatol

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SummaryKeloid disease (KD) is a common, benign, dermal fibroproliferative growth of unknown aetiology. Lesions tend to grow over time; they often recur following therapy and do not regress spontaneously. KD causes considerable discomfort due to pain, pruritus and inflammation, and a significant psychosocial impact with reduced quality of life. It is unique to humans and occurrence is higher in individuals with dark, pigmented, ethnic skin. There is a strong familial heritability, with a high ethnic predisposition in individuals of African, Asian and Hispanic descent. High recurrence rates and unknown resolution rates present a major problem for both the patient and clinician. Many treatment modalities exist; however, there is no single advocated therapy. Therefore, the aim of this review was to explore the most current literature regarding the range of treatment options for KD and to offer a structured approach in the management of KD, based on evidence and experience, to aid clinicians in their current practice. A focused history involving careful evaluation of the patient's symptoms, signs, quality of life and psychosocial well-being should direct targeted therapy, complemented with regular follow-up and re-evaluation. Many treatment modalities, such as intralesional steroid injection, silicone gel application, cryotherapy, lasers, 5-fluorouracil and, relatively recently, photodynamic therapy, are currently being used in clinical practice for the management of KD. Combination therapies have also been shown to be beneficial. However, there is a lack of robust, randomized, level-one, evidence-controlled trials evaluating these treatment options. Management of KD in ethnic pigmented skin remains a clinical challenge. Thus, a strategic approach with structured assessment, targeted therapy and focus on prevention of recurrence is highly recommended. Quality evidence is essential in order to tailor treatment effectively for the ethnic patient presenting with KD.What's already known about this topic?• Keloid disease (KD) is a common, benign, fibroproliferative tumour of unknown origin.• With high recurrence rates, treatment of KD remains a challenge for both the patient and clinician.• With lack of level-one evidence, there is no single advocated therapy.What does this study add?• A structured strategic approach for management of KD by utilizing a focused history, targeted therapy and regular follow-up of the patient.• Patients' symptoms, signs, quality of life and psychosocial well-being should be carefully evaluated and managed.

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Section: Surgical Excision and Adjuvant Therapymentioning

confidence: 99%

Strategic management of keloid disease in ethnic skin: a structured approach supported by the emerging literature

Uddin

Bayat

2013

Br J Dermatol

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“…The most common are the adverse effects of skin maceration and skin eruption, which have been reported in multiple studies. [75][76][77] All adverse effects resolved after discontinuing therapy without any adverse sequelae.…”

Section: Silicone Gelmentioning

confidence: 97%

“…In the treatment group, only 18 patients (27%) had formation of a nonphysiologic scar compared with the control group, where 25 patients (55%) had an altered scar. 75 Li-Tsang et al 76 evaluated the effects of silicone gel dressing and pressure therapy on posttraumatic hypertrophic scars. After 6 months of intervention, they concluded that SGS was more effective in alleviating pain and pruritus rather than scar thickness.…”

Section: Silicone Gelmentioning

confidence: 99%

“…In additional, tape stripping significantly increased the scar elevation index, epithelial thickness, and cellularity, while the occlusion group showed reductions in all the former factors. 74 In a randomized controlled trial by de Giorgi et al, 75 silicone gel was applied to 110 surgical incisions for 60 days after the removal of stitches. In the treatment group, only 18 patients (27%) had formation of a nonphysiologic scar compared with the control group, where 25 patients (55%) had an altered scar.…”

Section: Silicone Gelmentioning

confidence: 99%

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Scar Revision Review

Thomas

Somenek

2012

Arch Facial Plast Surg

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Scars are a natural part of dermal healing following lacerations, incisions, or tissue loss. They can vary in quality depending on the individual's racial characteristics, the mechanism of the trauma, and conditions in which the wound healed-all of which are factors beyond the surgeon's control. A scar on the face can have significant implications for the patient. What may seem like an insignificant issue to the casual observer can cause continuous frustration for the patient, affecting their daily lives. These can include psychological as well as social consequences, leading to a diminished quality of life. Factors that the surgeon can control include the favorable repositioning of the scar, proper alignment of the wound edges, and meticulous handling of the tissues.

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“…Eng verknüpft mit den Prinzipien der Dehnung kommt der Narbenbehandlung eine besondere Bedeutung zu -zumal in der reparativen Phase der Wundheilung und Reifung einer Narbe bewegungseinschränkendes und limitierendes Gewebe mit funktionellen Einbußen einhergeht [5,11].…”

Section: Narbenbehandlungunclassified

Nachbehandlung und Rehabilitation der komplexen Handverletzung

Blumenthal

2012

Trauma Berufskrankh

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The use of silicone gel in the treatment of fresh surgical scars: a randomized study

Abstract: The results of this study indicate that silicone gel is able to reduce the formation of keloid and hypertrophic scars and the signs/symptoms associated with the healing process (paraesthesia, pulling sensation, alterations in colour).

Cited by 44 publications

References 11 publications

Strategic management of keloid disease in ethnic skin: a structured approach supported by the emerging literature

Strategic management of keloid disease in ethnic skin: a structured approach supported by the emerging literature

Scar Revision Review

Nachbehandlung und Rehabilitation der komplexen Handverletzung

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