The Use of Silicones as Extractants of Biologically Active Substances from Vegetable Raw Materials

Abstract

Based on theoretical studies, the authors of this paper propose the use of cosmetic organosilicon polymers (commonly called silicones) for the extraction of a complex of biologically active substances contained in vegetable raw materials. It is important to note that the biological molecules do not interact with the organosilicones and, therefore, their properties are not altered after the extraction. In this work, we investigate the efficiency of several polyorganosiloxanes as extractants of vegetable raw materials (Calendula Officialis L. and Artemisia Absinthium L.) useful for the preparation of cosmetic emulsions. Specifically, the extraction studies were conducted by using polyorganosiloxanes with a single component (polydimethylsiloxane Silicone Oil 350 cSt, cyclopentasiloxane BRB CM 50, and phenyltrimethicone BRB PTM 20) as well as a mixture (PEG-12 polydimethylsiloxane BRB 526, a solution of dimethiconol in cyclopentasiloxane BRB 1834, and amodimethicone BRB 1288). Compared to water and ethyl alcohol, polyorganosiloxanes are more effective in the extraction of the biologically active substances that are contained in the raw plants. Interestingly, the combination of different polyorganosiloxanes improved the extraction efficiency. The attained knowledge can be helpful in the development of a novel protocol for the formulation of emulsions appealing for cosmetic applications.

Freeze-Dried Camelina Lipid Droplets Loaded with Human Basic Fibroblast Growth Factor-2 Formulation for Transdermal Delivery: Breaking through the Cuticle Barrier to Accelerate Deep Second-Degree Burn Healing

“…Plant raw materials have been recently used for numerous applications, including for the synthesis of anti-inflammatory products and cosmetic emulsions [37][38][39][40]. Among the natural materials, fatty vegetable oils (triglycerides) are valuable components of medicinal and decorative cosmetics.…”