Dental Caries 2021
DOI: 10.5772/intechopen.93518
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The Use of Silver Diamine Fluoride in Pediatric Dentistry

Abstract: This book chapter aims to discuss the main aspects related to the use of silver diamine fluoride (SDF) in Pediatric Dentistry. The composition and mechanism of action of the SDF are presented, as well as the application technique and indications. The effectiveness of SDF is reported based on contemporary scientific evidence from laboratory and clinical studies, focusing on its effect in enamel and dentin remineralization and caries arrestment. Parental and professional acceptance of tooth staining is presented… Show more

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Cited by 5 publications
(11 citation statements)
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“…The mechanism of action of SDF relies in its ability to react with hydroxyapatite to generate fluorapatite, which prevents or lessens any future caries. When SDF is administered, it penetrates both the enamel and dentin, stocking the tooth with nearly twice as much subsurface fluoride as other fluoride forms [ 12 ]. Additionally, SDF specifically inhibits matrix metalloproteinases, cathepsins, and bacterial collagenases, which break down the exposed dentine organic matrix.…”
Section: Introductionmentioning
confidence: 99%
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“…The mechanism of action of SDF relies in its ability to react with hydroxyapatite to generate fluorapatite, which prevents or lessens any future caries. When SDF is administered, it penetrates both the enamel and dentin, stocking the tooth with nearly twice as much subsurface fluoride as other fluoride forms [ 12 ]. Additionally, SDF specifically inhibits matrix metalloproteinases, cathepsins, and bacterial collagenases, which break down the exposed dentine organic matrix.…”
Section: Introductionmentioning
confidence: 99%
“…Because of this effect, the SDF has not been accepted widely. To decrease this negative effect, two alternatives exist, first one which is using the potassium iodide (KI) to mask staining and the other alternative is to apply glass ionomer or resin composite restoration over SDF to improve the aesthetics of the tooth after SDF application [ 12 ].…”
Section: Introductionmentioning
confidence: 99%
“…Additionally, it is used as a desensitizing agent [ 16 ]. It is an efficient, effective, and inexpensive agent [ 17 ]. It can also be used as an alternative to restorative treatment in case of pandemics as what had been advised in COVID-19 to minimize the spread of aerosols [ 18 , 19 ].…”
Section: Introductionmentioning
confidence: 99%
“…1 It can be prevented and arrested using fluoride-based materials like Silver Diamine Fluoride (SDF) which is a noninvasive approach to halt the progression of carious lesion. 2,3 SDF is a colorless alkaline liquid containing 255,000 ppm of silver and 44,800 ppm fluoride ion at pH 10. Its composition is 25% silver, 8% ammonia, 5% fluoride, and 62%v water.…”
Section: Introductionmentioning
confidence: 99%