The use of single port surgery for polyps located in the rectum

Transanal Endoscopic Microsurgery (TEM) Facilitated by Video‐Assistance and Anal Insertion of a Single‐Incision Laparoscopic Surgery (SILS®)‐Port: Preliminary Experience

“…Transanal excision of rectal adenomas via a laparoscopic single access port device was described for the first time in 2010 by Khoo et al andDemirbas et al (accepted 2010, published 2012) [13,14]. Several case reports [15,16] and case series followed, investigating different laparoscopic single port devices [10,12,[17][18][19].…”

Synthesis, Characterization and Anti‐inflammatory Activity of 5‐{[((5‐Substituted‐aryl)‐1,3,4‐thiadiazol‐2‐yl)thio]‐n‐alkyl}‐1,3,4‐oxadiazole‐2‐thiol

“…Recently, synthetic chemists have accepted that chemical modification of this functional group could possibly improve the safety profile of these drugs. 1 Synthesis of various derivatives of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles has been attracting wide attention due to their wide spectrum of biological activities, [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16] such as antimicrobial, antimycobacterial, antifungal, antidepressive, antiviral, analgesic, anti-inflammatory, antitumor, vascular smooth muscle relaxant and cardiovascular activity. It was therefore considered worthwhile to replace free carboxylic acid group of nonsteroidal antinflammatory drugs by these basic nuclei along with a S(CH 2 ) n bridge to study the effect on biological activity.…”

Transanal minimally invasive surgery with single-port (TAMIS) for the management of rectal neoplasms: a pilot study

“…This technique has proven to be effective and safe in treating early rectal tumors and polyps. When compared with traditional techniques as local excision, TEM has the advantages of better visualization of the rectum, access to higher lesions and better ability to obtain clear margins with the possibility of excision without fragmentation of the surgical specimen [1][2][3][4][5][6][7][8][9][10][11][12][13] . The high cost of the equipment and surgical instruments added to the limited number of indications for its use, consequently, lead to a long learning curve.…”