2023
DOI: 10.3390/biomedicines11092507
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The Use of Small-Molecule Compounds for Cell Adhesion and Migration in Regenerative Medicine

Juan Mitchell,
Kevin W.-H. Lo

Abstract: Cell adhesion is essential for cell survival, communication, and regulation, and it is of fundamental importance in the development and maintenance of tissues. Cell adhesion has been widely explored due to its many important roles in the fields of tissue regenerative engineering and cell biology. This is because the mechanical interactions between a cell and its extracellular matrix (ECM) can influence and control cell behavior and function. Currently, biomaterials for regenerative medicine have been heavily i… Show more

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Cited by 1 publication
(2 citation statements)
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“…The corresponding numerical procedure either solves a set of the dynamic equations for the particular segment, if these threshold conditions are not satisfied, or shifts this elastic segment together with the contacting ball surface, moving according to its own motion. The adhesion indicators are defined (in the same dimensionless units as above) by the distance equal to the unit, as well as the mutual difference of the velocities between the individual automata and indenter δv crit =|V x |= 1 and the critical force caused by their displacements from the equilibrium (original) distances f crit = K 0 δ|x − x 0 | = 3, where K ij ≡ K 0 is the effective elastic constant in Equation (5).…”
Section: Numerical Modelmentioning
confidence: 99%
See 1 more Smart Citation
“…The corresponding numerical procedure either solves a set of the dynamic equations for the particular segment, if these threshold conditions are not satisfied, or shifts this elastic segment together with the contacting ball surface, moving according to its own motion. The adhesion indicators are defined (in the same dimensionless units as above) by the distance equal to the unit, as well as the mutual difference of the velocities between the individual automata and indenter δv crit =|V x |= 1 and the critical force caused by their displacements from the equilibrium (original) distances f crit = K 0 δ|x − x 0 | = 3, where K ij ≡ K 0 is the effective elastic constant in Equation (5).…”
Section: Numerical Modelmentioning
confidence: 99%
“…Furthermore, the adhesive technologies have found extensive use in wide range of practically important application areas, for example, in robotics [1][2][3] and medicine [4,5]. The adhesive properties of contacting surfaces play a decisive role in such common technological processes as painting [6,7], soldering [8,9], welding [10,11], gluing surfaces [12,13], coatings [14], etc.…”
Section: Introductionmentioning
confidence: 99%