The Use of Stellate Ganglion Block in the Treatment of Panic/Anxiety Symptoms with Combat‐Related Post‐Traumatic Stress Disorder; Preliminary Results of Long‐Term Follow‐Up: A Case Series

Mulvaney, Sean W.; McLean, Brian; Leeuw, Jason De

doi:10.1111/j.1533-2500.2010.00373.x

Cited by 57 publications

(55 citation statements)

References 27 publications

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“…Reduction of NE following SGB has been shown in a human model by [34]. Thus the cascade is reversed, NE levels are reduced leading to reduction or elimination of PTSD symptoms [35][36][37]. …”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Post Traumatic Stress Disorder (PTSD) as an Over Activation of Sympathetic Nervous System: An Alternative View

Lipov¹

2013

J Trauma Treat

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Section: Discussionmentioning

confidence: 99%

“…Clinical results have been very encouraging. The institutions were: Walter Reed National Medical Center (Mulvaney 2010), Naval Medical Center San Diego [21], Tripler Army Medical Center [22], and Advanced Pain Centers [20,23,24]. Preliminary effectiveness rate seems to be 60 to 75 % [24].…”

Section: Stellate Ganglion Block ( Sgb)mentioning

confidence: 99%

Post Traumatic Stress Disorder (PTSD) as an Over Activation of Sympathetic Nervous System: An Alternative View

Lipov¹

2013

J Trauma Treat

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“…Results from subsequent confirmatory trials of the effectiveness of the SGB in reducing PTSD symptoms were published by Mulvaney [23], Lipov et al (2011) [24], Hicky et al (2012) [25] and Lipov et al (2012) [26]. The specific pathways by which SGB using local anesthetic modulates NGF and NE are summarized next.…”

Section: The Role Of Cort In Post-traumatic Stress Disorder Developmentmentioning

confidence: 96%

Modulation of NGF by cortisol and the Stellate Ganglion Block – Is this the missing link between memory consolidation and PTSD?

et al. 2012

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“…1 In addition, this procedure has been performed increasingly for non-painful conditions. [2][3][4] The common techniques for SGB are the paratracheal approaches performed at the level of the transverse process of the sixth (C6) or the seventh cervical vertebra (C7). 5,6 These techniques are conventionally guided by the use of anatomic landmarks and/or fluoroscopy, 4,7 but both of these techniques can be associated with complications.…”

Section: Résumémentioning

confidence: 99%

Evaluation of sonoanatomy relevant to performing stellate ganglion blocks using anterior and lateral simulated approaches: an observational study

Bhatia

Flamer

Peng

2012

Can J Anesth/J Can Anesth

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Purpose Stellate (cervicothoracic) ganglion block (SGB) can be associated with serious complications, such as esophageal and vascular injury. The objective of this study was to evaluate the potential for vascular and esophageal injury in healthy subjects by examining the sonoanatomy of the neck relevant to the SGB at the sixth (C6) and seventh (C7) cervical vertebral levels and determining the incidence of blood vessels and esophagi in the simulated path of needle insertion in the conventional and two different ultrasound-guided approaches used to perform a SGB. Methods Ultrasound scanning of the neck at the C6 and C7 cervical vertebral levels was performed in 100 adult subjects, and the following measurements were obtained: the degree of deviation of the esophagus relative to the larynx/trachea; the likelihood of encountering a vessel in the simulated path of needle insertion in the two different approaches to SGB; the incidence of the vertebral artery being situated outside the foramen transversarium at the C6 level; and the distance of the simulated path of needle insertion in the anterior and lateral approaches to SGB at the C6 level. Results The position of the esophagus was found to be variable but lateral to the airway in 50% and 74% of the subjects at C6 and C7, respectively. The esophagus covered more than half of the distance between the airway and the carotid artery in 14% and 44% of the subjects at the C6 and C7 levels, respectively. With the anterior approach, a major vessel was observed in up to 29% and 43% of patients at the C6 and C7 levels, respectively. The vertebral artery was outside the foramen transversarium in 7% of subjects at the C6 level. Conclusion Major blood vessels and the esophagus are in close proximity to needle pathways during the anterior approach to SGB performed with either anatomic landmarking or fluoroscopic guidance. An ultrasound-guided lateral approach at the C6 level may possibly confer a greater margin of safety for performing SGB. RésuméObjectif Le bloc du ganglion stellaire (cervicothoracique) (BGS) peut eˆtre associe´a`des complications graves, telles que des le´sions oesophagiennes et vasculaires. Les objectifs de l'e´tude e´taient les suivants : e´tudier l'e´cho-anatomie du cou pertinente pour le BGS au niveau des 6 e et 7 e verte`bres cervicales (C6 et C7) chez des patients en bonne sante´, e´valuer le risque de le´sion vasculaire et oesophagienne en enregistrant l'incidence des vaisseaux sanguins et de This study was conducted with written informed consent from the study subjects. This report describes an observational clinical study, and it adheres to the STROBE guidelines.

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The Use of Stellate Ganglion Block in the Treatment of Panic/Anxiety Symptoms with Combat‐Related Post‐Traumatic Stress Disorder; Preliminary Results of Long‐Term Follow‐Up: A Case Series

Abstract: Selective blockade of the right stellate ganglion at C6 level is a safe and minimally invasive procedure that may provide durable relief from PTSD symptoms, allowing the safe discontinuation of psychiatric medications. blacksquare, square, filled.

Cited by 57 publications

References 27 publications

Post Traumatic Stress Disorder (PTSD) as an Over Activation of Sympathetic Nervous System: An Alternative View

Post Traumatic Stress Disorder (PTSD) as an Over Activation of Sympathetic Nervous System: An Alternative View

Modulation of NGF by cortisol and the Stellate Ganglion Block – Is this the missing link between memory consolidation and PTSD?

Evaluation of sonoanatomy relevant to performing stellate ganglion blocks using anterior and lateral simulated approaches: an observational study

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