The use of testosterone propionate in the treatment of dysmenorrhea

Rubinstein, H. S.; Abarbanel, A. R.

doi:10.1016/s0002-9378(15)31567-2

Cited by 17 publications

(5 citation statements)

References 15 publications

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“…Rubinstein et al. showed that TP improved the management of patients with dysmenorrhea— a condition frequently associated with meno‐metrorrhagia [50]. The authors believed that pain associated with dysmenorrhea was the result of an endocrine imbalance, with either excess estrogen or reduced progesterone levels, leading to excessive contractions of the myometrium.…”

Section: Androgen Therapy Of Dysmenorrheamentioning

confidence: 99%

“…Rubinstein et al. provided vivid descriptions of how TP treatment improved management of patients with dysmenorrhea [50]. The following is an example of the symptoms that one patient had prior to treatment:…”

Section: Androgen Therapy Of Dysmenorrheamentioning

confidence: 99%

“…Nausea, occasional vomiting, insomnia, and feelings of depression and anxiety accompanied the pain during the first one or two days. [50]…”

Section: Androgen Therapy Of Dysmenorrheamentioning

confidence: 99%

“…She lost no time from work during this period, since she was free from digestive upsets, sleep disturbances, and the usual feelings of depression. [50]…”

Section: Androgen Therapy Of Dysmenorrheamentioning

confidence: 99%

“…This was given on the twenty‐fifth day and was followed the next day by menstruation which was accompanied by marked abdominal pain, nausea, and vomiting. [50]…”

Section: Androgen Therapy Of Dysmenorrheamentioning

confidence: 99%

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Testosterone Therapy in Women with Gynecological and Sexual Disorders: A Triumph of Clinical Endocrinology from 1938 to 2008

Traish

Feeley

Guay

2009

The Journal of Sexual Medicine

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Introduction Although the term “medicalization” has been used by some to describe contemporary testosterone use in women with sexual disorders and testosterone deficiency syndrome, testosterone therapy for women with various gynecological and sexual disorders has been practiced since the late 1930s. Aim The study aimed to perform a historical review of testosterone use in women with sexual and gynecological disorders. This review is necessary to bridge important knowledge gaps in the clinical use of testosterone in women with sexual health concerns and to provoke new thoughts and understanding of the multidisciplinary role of testosterone in women’s overall health. Methods Review of medical literature on androgen therapy in women was carried out from 1938 through 2008. Results Approximately 70 years ago, clinicians from various disciplines relied on personal experience and clinical observations for outcome assessment of testosterone therapy in women. These early reports on testosterone use in women with sexual medical problems served as a foundation for the development of contemporary approaches and subsequent testosterone treatment regimens. Testosterone use was reported for sexual dysfunction, abnormal uterine bleeding, dysmenorrhea, menopausal symptoms, chronic mastitis and lactation, and benign and malignant tumors of the breast, uterus, and ovaries. Conclusions Health-care professionals engaged in the management of women’s health issues have observed the benefits of androgen therapy throughout much of the 20th century. Despite this clinical use of testosterone in women for more than seven decades, contemporary testosterone therapy in women is hotly debated, misunderstood, and often misrepresented in the medical community.

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Section: Androgen Therapy Of Dysmenorrheamentioning

confidence: 99%

Section: Androgen Therapy Of Dysmenorrheamentioning

confidence: 99%

“…Nausea, occasional vomiting, insomnia, and feelings of depression and anxiety accompanied the pain during the first one or two days. [50]…”

Section: Androgen Therapy Of Dysmenorrheamentioning

confidence: 99%

“…She lost no time from work during this period, since she was free from digestive upsets, sleep disturbances, and the usual feelings of depression. [50]…”

Section: Androgen Therapy Of Dysmenorrheamentioning

confidence: 99%

“…This was given on the twenty‐fifth day and was followed the next day by menstruation which was accompanied by marked abdominal pain, nausea, and vomiting. [50]…”

Section: Androgen Therapy Of Dysmenorrheamentioning

confidence: 99%

See 3 more Smart Citations