The review article is devoted to the history of creation, biological effects and clinical application of the entomological drug Adenoprosin. The data of experimental studies are presented, indicating a high biological activity of the drug, the mechanisms of its therapeutic action are described. The pharmacological effects of Adenoprosin were analyzed, which ensure its high clinical efficacy and good tolerability. The pathogenetic validity of the appointment of Adenoprosin in patients with chronic prostatitis and benign prostatic hyperplasia was shown.