The use of the mesher to improve split‐thickness skin graft survival

Colman, Marc F.; Gurucharri, Michael

doi:10.1288/00005537-198702000-00019

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Citrate is added as a chelating agent to packed red blood cells to prevent coagulation. An even more dramatic example is the skin graft mesher and tissue expander routinely used by plastic surgeons to promote vascularization and cell growth in order to achieve better outcomes in larger wound beds (Colman and Gurucharri, 1987 ). If the term “biomaterial” refers to the introduction of synthetic material to aid the regenerative process by providing a biomolecular and spatial environment conducive to cell proliferation and vascularization, then could not the ubiquitous Band-Aid, the common suture, or the vascular stent be considered elements of RM/TE?…”

Section: Discussionmentioning

confidence: 99%

Tissue Engineering and Regenerative Medicine: Semantic Considerations for an Evolving Paradigm

Katari

Peloso

Orlando

2015

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

Tissue engineering (TE) and regenerative medicine (RM) are rapidly evolving fields that are often obscured by a dense cloud of hype and commercialization potential. We find, in the literature and general commentary, that several of the associated terms are casually referenced in varying contexts that ultimately result in the blurring of the distinguishing boundaries which define them. “TE” and “RM” are often used interchangeably, though some experts vehemently argue that they, in fact, represent different conceptual entities. Nevertheless, contemporary scientists have a general idea of the experiments and milestones that can be classified within either or both categories. Given the groundbreaking achievements reported within the past decade and consequent watershed potential of this field, we feel that it would be useful to properly contextualize these terms semantically and historically. In this concept paper, we explore the various definitions proposed in the literature and emphasize that ambiguous terminology can lead to misplaced apprehension. We assert that the central motifs of both concepts have existed within the surgical sciences long before their appearance as terms in the scientific literature.

show abstract

Section: Discussionmentioning

confidence: 99%