The Use of Umbilical Cord Blood for Autologous Transfusion in Neonatal Open Heart Surgery

Fernandez, Adam; Chasovskyi, Kyrylo

doi:10.1053/j.jvca.2019.05.007

Cited by 5 publications

(1 citation statement)

References 49 publications

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“…An intriguing option is to use autologous umbilical cord blood (collected at birth in prenatally diagnosed CHD) for autotransfusion in neonatal heart surgery. Although anecdotal cases exist of the plausibility, issues of collection, storage, timing of surgery (amongst others) need clarification as evidence is gathered to establish its future role ( 59 ).…”

Section: Blood Tests and Hemostasismentioning

confidence: 99%

Blood Conservation and Hemostasis Management in Pediatric Cardiac Surgery

Sebastian

Ahmed

2021

Front. Cardiovasc. Med.

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Pediatric cardiac surgery is associated with significant perioperative blood loss needing blood product transfusion. Transfusion carries serious risks and implications on clinical outcomes in this vulnerable population. The need for transfusion is higher in children and is attributed to several factors including immaturity of the hemostatic system, hemodilution from the CPB circuit, excessive activation of the hemostatic system, and preoperative anticoagulant drugs. Other patient characteristics such as smaller relative size of the patient, higher metabolic and oxygen requirements make successful blood transfusion management extremely challenging in this population and require meticulous planning and multidisciplinary teamwork. In this narrative review we aim to summarize risks and complications associated with blood transfusion in pediatric cardiac surgery and also to summarize perioperative coagulation management and blood conservation strategies.

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Section: Blood Tests and Hemostasismentioning

confidence: 99%