The Use Op Sulfanilylguanidine in Surgical Patients

Firor, Warfield M.; Jonas, August F.

doi:10.1097/00000658-194107000-00004

Annals of Surgery

1941

DOI: 10.1097/00000658-194107000-00004

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The Use Op Sulfanilylguanidine in Surgical Patients

Warfield M. Firor¹,

August F. Jonas²

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1942

1982

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Cited by 29 publications

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“…In 1940, Dr. Warfield M. Firor was using sutfanilylguanidine to sterilize the enteric tract [3]. I was studying the role of bacteria in intestinal obstruction and immediately began administering this compound to dogs, hoping to sterilize the enteric tract.…”

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confidence: 99%

Historical development of intestinal antisepsis

Poth

1982

World j. surg.

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The study of intestinal antisepsis has been the concern of the author for the past 40 years. Pioneer studies of sulfanilamide, sulfanilylguanidine, succinylsulfanilamide, succinylsulfathiazole, and phthalylsulfathiazole in dogs are reported, and subsequent clinical trials are detailed. By 1948, intestinal antisepsis had become an established procedure to complement adequate mechanical cleansing. Careful attention to meticulous, gentle handling of tissues, preservation of maximum blood supply, and strict aseptic technique should be continued; intestinal antisepsis is not a substitute for surgical principles. A combination of neomycin‐phthalylsulfathiazole, together with the above‐named practices, has resulted in an abdominal wall wound infection rate below 3%, with no intra‐abdominal complications due to postoperative infection.

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mentioning

confidence: 99%

Historical development of intestinal antisepsis

Poth

1982

World j. surg.

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Eruption Due to Sulfanilylguanidine (Sulfaguanidine)

Ringelman¹

1942

Arch Dermatol

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Bacteriostatic Properties of Sulfanilamide and Some of Its Derivatives

Poth¹,

Knotts²,

Lee³

et al. 1942

Arch Surg

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The Use Op Sulfanilylguanidine in Surgical Patients

Cited by 29 publications

References 0 publications

Historical development of intestinal antisepsis

Historical development of intestinal antisepsis

Eruption Due to Sulfanilylguanidine (Sulfaguanidine)

Bacteriostatic Properties of Sulfanilamide and Some of Its Derivatives

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