This study has focused on the effective media, organizations, celebrities, politicians, and ordinary people that are interested in climate change across Twitter. A quantitative content analysis based on the cross-sectional analysis method was performed to assess (1,277,833) tweets from 21st Nov to 10th Dec 2016, which was close to the implementation of Paris Agreement on 4th Nov 2016. The study concluded that positive sentiments and attitudes were dominant compared to negatives, particularly toward media and scientific frames. However, neutral frames formed the biggest frame. This study recommends the unification of the efforts and the declaration of clear views and practical actions by all bodies such as scientists, celebrities, politicians, ordinary people, media, organizations including scientific institutions and centers to construct common knowledge, and evidence through variety ways so as to achieve the highest rate of raising awareness among people worldwide.