The utility of 2-[18F]FDG-PET/CT maximum SUV versus CT attenuation for directing bone biopsies

Sebro, Ronnie; Ashok, Subha

doi:10.1007/s00330-021-07770-8

Cited by 1 publication

(1 citation statement)

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“…SUVmax, was calculated by the ratio of maximum uptake by the metastatic lesion to surrounding normal bony tissue. 15 In PET/CT, SUVmax is commonly determined for assessing the lesion's metabolic activity, and it can help differentiate benign lesions from malignant ones. Further, it can assess if the tumour is aggressive or not.…”

Section: Discussionmentioning

confidence: 99%

Comparison of 18-FDG SUV Value with Bone Scintigraphy Findings in Diagnosed Cases of Malignancy with Sclerotic Bony Metastasis

Waqar

Siddiqui

Mannan

et al. 2022

PAFMJ

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Objective: To determine the correlation of 18F-FDG SUV value with bone scintigraphy findings, i.e. uptake of Tc-99m in diagnosed cases of malignancy with sclerotic bone metastasis. Study Design: Prospective longitudinal study. Place and Duration of Study: Armed Forces Institute of Radiology and Imaging, Rawalpindi Pakistan, from Sep 2020 to Mar 2021. Methodology: This study included 30 patients of age 18 to 80 years who had sclerotic bone metastasis as confirmed in histopathology. All patients underwent whole-body PET/CT scanning to evaluate sclerotic bone metastasis and determined 18-FDG SUV after 5MBq/kg body weight of 18-FDG was injected. After two weeks of PET/CT scan, Tc-99m bone scintigraphy was carried out, and SUV of Tc-99m was determined after 20-25mCi technetium-99 methylene disphosphonate was injected, and the correlation was assessed between SUV of 18-FDG and Tc-99m. Results: The mean 18-FDG SUVmax and mean Tc-99m SUVmax, were, 21.31±8.77g/ml and 15.29±6.49g/ml respectively.21(70%) lesions on 18-FDG PET/CT and 8(26.7%) on Tc-99m bone scintigraphy were metastatic in bones. 18-FDG SUV on PET/CET and Tc-99m SUV on bone scintigraphy correlated positively with each other, and this correlation was found to be statistically significant (r=0.491, p=0.006). Conclusion: 18-FDG SUV PET/CT significantly correlated with Tc-99m SUV on bone scintigraphy and helped detect metastatic lesions earlier and modulate treatment response.Keywords: Bone metastasis, Bone scintigraphy, 18-FDG PET/CT, Tc-99m SUV.

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Section: Discussionmentioning

confidence: 99%