Qualitative research methods have treated Western knowledge systems and Indigenous studies as polar opposites with asymmetrical power relations. Studies have documented the hegemonic dominance of Western science over Indigenous knowledge systems. Despite this tension, there is an opportunity to integrate Western science with Indigenous knowledges to bridge these discordant systems. This paper argues that Constructivist Grounded Theory (CGT), a Western-based version of grounded theory can be weaved with Indigenous research. CGT’s emphasis on co-construction, relationality, value-free inquiry, and social justice align with Indigenous research principles. Using examples from both CGT and Indigenous scholarship, the paper argues that CGT with its pragmatist and constructivist orientation can exist alongside an Indigenous research agenda. Furthermore, the flexible, emergent, and relativist nature of CGT aligns with some aspects of Indigenous research. The paper demonstrates that both knowledge systems can be treated on an equal par, engender methodological reciprocity and provide mutual benefits to each other. Weaving CGT and Indigenous research might provide new avenues of thinking about doing research with Indigenous communities and other marginalized communities.