The Utility of Dermatoscopy in the Evaluation of Xanthogranulomas

Hussain, Sarwat; Kozic, Heidi; Lee, Jason B.

doi:10.1111/j.1525-1470.2008.00748.x

Cited by 21 publications

(21 citation statements)

References 3 publications

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“…[114][115][116] Moreover, some linear and/or branched vessels may be present. Specific features include brownish globules and dots of dermal hemosiderin in reticulohistiocytoma, peripheral pigmented network with basal hyperpigmentation in xanthomized dermatofibroma, isolated dotted vessels, corresponding to dilated capillaries, and ''cloud'' of yellow areas in adult xanthogranuloma.…”

Section: Xanthomatous Neoplasmsmentioning

confidence: 99%

Dermatoscopy: Alternative uses in daily clinical practice

Micali

Lacarrubba

Massimino

et al. 2011

Journal of the American Academy of Dermatology

178

110

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Section: Xanthomatous Neoplasmsmentioning

confidence: 99%

Dermatoscopy: Alternative uses in daily clinical practice

Micali

Lacarrubba

Massimino

et al. 2011

Journal of the American Academy of Dermatology

178

110

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“…1,2 The most characteristic dermoscopic features of JXG have been described as 'setting sun' appearance. 3,4 Additional features include 'clouds' of paler yellow globules, which represent the collection of lipid-laden histiocytes in superficial dermis. The subtle pigment network and whitish streak indicate foci of fibrosis.…”

Section: Introductionmentioning

confidence: 99%

Structural correlations between dermoscopic and histopathological features of juvenile xanthogranuloma

Song

et al. 2011

Acad Dermatol Venereol

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Juvenile xanthogranuloma(JXG) is the variant of non-Langerhans' cell histiocytosis. The orange-yellow background coloration with clouds of paler yellow deposits is the most characteristic dermoscopic finding of JXG. Other dermoscopic features include erythematous border, subtle pigment network and white linear streak. The objective of this study was to present the structural correlation between dermoscopic features and histopathological findings of JXG and to find the different dermoscopic features in various stages of JXG. Eleven patients with histologically proven JXG were examined with polarized light dermoscopy. Histopathological findings were assessed and dermoscopic features including setting sun appearance, clouds of paler yellow globules, whitish streak, and branched and linear vessels were evaluated. Among 11 patients, five patients were in early evolutionary stage, four patients in fully developed stage and two in late regressive stage. The setting sun appearance was found in all patients in different stages except one in late regressive stage (90.9%). The clouds of paler yellow globules were present in nine patients (81.8%) and were constant features in fully developed stage and late regressive stage. The whitish streak was present in four patients (36.4%) and telangiectasia in 10 patients (81.8%). The setting sun appearance may hold diagnostic value in early evolutionary stage to fully developed stage, but not in late regressive stage. The clouds of paler yellow globules are more predominant in fully developed stage and late regressive stage. In addition to the use of dermoscopy as an accurate diagnostic tool for differential diagnosis, it could be applied in evaluation of histopathological maturation of JXG.

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“…Le XGJ se manifeste en dermoscopie par la présence d'un fond jaune-orangé, correspondant aux histiocytes chargés de lipides. Parfois, le centre est typiquement plus clair avec des images « nuageuses » [1,2] comme dans le cas de la lésion du dos de notre patiente. Un aspect de fibrose peut être observé au sein des lésions plus anciennes.…”

Section: Discussionunclassified

“…3) montrait une coloration jaune-orangé homogène du fond, avec un fin liséré érythémateux en périphérie, donnant une image de « coucher de soleil » [1,2]. Au centre de la lésion, on trouvait un pseudoréseau inversé blanchâtre, correspondant à la fibrose du derme papillaire, ainsi que quelques microhémorragies aspécifiques.…”

Section: Dermoscopieunclassified