The utility of MR in planning the radiation therapy of oligodendroglioma

Shuman, W P; Br, Griffin; Dr, Haynor; Dc, Jones; Js, Johnson; Cromwell, Laurence D.; Ge, Laramore

doi:10.2214/ajr.148.3.595

Cited by 16 publications

(3 citation statements)

References 13 publications

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“…The tumor may not be visualized on CT images (34). MR imaging is superior to CT in defining the full extent of tumor involvement (81). The tumor is usually hypointense compared to gray matter on T1-weighted images and hyperintense compared to gray matter on T2-weighted images (Figs 4, 6, 7) (79).…”

Section: Imaging Featuresmentioning

confidence: 99%

Oligodendroglioma and Its Variants: Radiologic-Pathologic Correlation

Koeller¹,

Rushing²

2005

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121

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Oligodendroglioma is the third most common glial neoplasm and most commonly arises in the frontal lobe. It occurs in males more frequently, and the peak manifestation is during the 5th and 6th decades. Children are affected much less commonly. The clinical presentation is often of several years duration with most patients presenting with seizures, reflecting the strong predilection of this tumor to involve the cortical gray matter. Current histopathologic classification schemes recognize two main types of tumors: well-differentiated oligodendroglioma and its anaplastic variant. Less commonly, neoplastic mixtures of both oligodendroglial and astrocytic components occur and are termed oligoastrocytomas, with both well-differentiated and anaplastic forms. Surgical resection is the mainstay of initial treatment, and many patients experience a long progression-free period. Recent genotyping has revealed chromosomal loss of 1p and 19q as a genetic signature in most oligodendrogliomas, and these tumors respond favorably to chemotherapy. Hence, radiation therapy is now generally reserved for partially resected tumors and cases that failed to benefit from chemotherapy. At cross-sectional imaging, the tumor characteristically involves the cortical gray matter and frequently contains calcification. Robust enhancement is not a common feature and suggests transformation to a higher histologic grade. Advanced magnetic resonance imaging techniques and metabolic imaging play increasingly important roles in both pre- and postoperative assessment of these complex neoplasms.

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Section: Imaging Featuresmentioning

confidence: 99%

Oligodendroglioma and Its Variants: Radiologic-Pathologic Correlation

Koeller¹,

Rushing²

2005

RadioGraphics

121

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“…The tumour may not be visualized on CT images [19] . MR imaging is superior to CT in defining the full extent of tumour involvement [23] . The tumor is usually hypointense compared to gray matter on T1-weighted images and hyperintense compared to gray matter on T2-weighted images [18] .…”

Section: Discussionmentioning

confidence: 99%

Anaplastic Oligodendroglioma in an Adolescent Male; A rare case Report and Review of the Literature

Saraswat¹,

Bharadwaj²,

Kumar³

et al. 2017

AIMDR

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“…T1-weighted sequences rely on the T1-shortening property of the gadolinium ion, which is how GBCAs were used the first 20 years after FDA approval. [30][31][32][33] During follow-up, imaging helps to monitor progression and response as well as to evaluate for posttreatment complications. The GBCA T1-shortening property causes faster longitudinal magnetization recovery and therefore greater MR signal intensity (enhancement) in the tissue compared to noncontrasted images.…”

Section: Contrast Media In Neuroimagingmentioning

confidence: 99%