The utility of nasal nitric oxide in the diagnostic evaluation of primary ciliary dyskinesia
Katherine A. Carr,
Paul E. Moore,
Michael G. O'Connor
Abstract:BackgroundThere is no gold‐standard test for primary ciliary dyskinesia (PCD), rather American Thoracic Society guidelines recommend starting with nasal nitric oxide (nNO) in children ≥5 years old and confirming the diagnosis with genetic testing or ciliary biopsy with transmission electron microscopy (TEM). These guidelines have not been studied in a clinical setting. We present a case series describing the PCD diagnostic process at our pediatric PCD center.MethodsDiagnostic data from 131 patients undergoing … Show more
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