The utility of obesity polygenic risk scores from research to clinical practice: A review
Philip R. Jansen,
Niels Vos,
Jorrit van Uhm
et al.
Abstract:SummaryObesity represents a major public health emergency worldwide, and its etiology is shaped by a complex interplay of environmental and genetic factors. Over the last decade, polygenic risk scores (PRS) have emerged as a promising tool to quantify an individual's genetic risk of obesity. The field of PRS in obesity genetics is rapidly evolving, shedding new lights on obesity mechanisms and holding promise for contributing to personalized prevention and treatment. Challenges persist in terms of its clinical… Show more
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