The Utility of Oscillometry for Assessing Treatment Responsiveness in Patients With Asthma Attacks

Takahashi, Shingo; Shirai, Toshihiro; Nakayasu, Hiromasa; Tamura, Kanami; Masuda, Toshihiro; Oishi, Kyohei; Kishimoto, Yutaro; Saigusa, M; Akamatsu, Taisuke; Yamamoto, Akito; Morita, Satoru; Asada, Kazuhiro

doi:10.1016/j.chest.2020.08.063

Cited by 1 publication

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“…In a study of patients with severe asthma, static lung hyperinflation measured by body plethysmography was strongly associated with peripheral airways dysfunction measured by oscillometry with improved X5 and residual volume/total lung capacity (RV/TLC) ratio observed after 12 months of biologic treatment [46 ▪ ]. Oscillometry is also feasible to perform in adults or children during an acute asthma exacerbation and improves along with symptoms following treatment [47,48]. An interesting potential application of oscillometry is the personalization of inhaler type for specific asthma phenotypes.…”

Section: Peripheral Airways Dysfunction Symptoms and Response To Trea...mentioning

confidence: 99%

The role of oscillometry in asthma

Donohue,

Kaminsky

2024

Current Opinion in Pulmonary Medicine

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Purpose of review Oscillometry is a noninvasive pulmonary function test that has gained significant interest in the evaluation of lung disease. Currently, oscillometry is primarily a research tool, but there is a growing body of evidence supporting its clinical use. This review describes the recent work evaluating the role of oscillometry in the diagnosis and treatment of asthma. Recent findings A large body of observational data supports the ability of oscillometry to distinguish healthy individuals from those with respiratory symptoms or lung disease. Oscillometry may not be as useful as an isolated diagnostic test in asthma, but the combination with other pulmonary function tests may improve its diagnostic ability. Oscillometry can detect peripheral airways dysfunction in asthma, which is associated with symptoms and the risk for exacerbations. To help guide future research, minimal clinically important differences for specific oscillometry variables have been developed. Oscillometry may be useful in monitoring the response to biological therapy and has potential for personalizing treatment for individual patients. Oscillometry also has potential in uncovering unique aspects of the pathophysiology of asthma in obesity. Summary Oscillometry is a promising tool in the diagnosis and management of asthma. More research is needed to support its routine clinical use.

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Section: Peripheral Airways Dysfunction Symptoms and Response To Trea...mentioning

confidence: 99%