The validity and reliability of continuous-wave near-infrared spectroscopy for the assessment of leg blood volume during an orthostatic challenge

Stone, Keeron; Fryer, Simon M; Ryan, Terrence; Stoner, Lee

doi:10.1016/j.atherosclerosis.2016.06.030

Cited by 37 publications

(45 citation statements)

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“…For each time point (10 min, 90 min, 170 min, post-), data were averaged over 30 s and expressed relative to supine baseline. Our laboratory has previously reported that the Portalite device is able to monitor changes in tHb with acceptable validity and reliability (intraclass correlation, ICC, range: 0.75-0.98; Lucero et al, 2017;Stone, Fryer, Ryan, & Stoner, 2016) and changes in TSI with acceptable reliability (ICC: 0.7-0.9; Lucero et al, 2017).…”

Section: Calf Blood Volumementioning

confidence: 99%

Effects of acute prolonged sitting on cerebral perfusion and executive function in young adults: A randomized cross‐over trial

et al. 2019

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Exposure to acute prolonged sitting reportedly leads to decreased cerebral blood flow. However, it is unclear whether this exposure translates to decreased cerebral perfusion and executive function or whether simple strategies to break up sitting can maintain cerebral perfusion and executive function. This study sought to answer two questions: in young, healthy adults, (a) does prolonged (3 hr) sitting lead to decreased cerebral perfusion and executive function? and (b) does breaking up prolonged sitting, using intermittent calf raise exercises, prevent changes in cerebral perfusion and executive function? Twenty young, healthy participants (21.7 [2.5] years, 70% female, 25.5 [6.1] kg/m2) were randomized to 3 hr sitting with 10 calf raises every 10 min (CALF) and 3 hr sitting without intermittent calf raises (CON). Prefrontal cortex perfusion was assessed using near‐infrared spectroscopy to monitor total hemoglobin (tHB) concentration and tissue saturation index (TSI, oxygenated hemoglobin). Executive function was assessed using the Stroop word and color tasks. Following 3 hr sitting, tHb was significantly lower in CALF versus CON (−2.1 μM, 95% CI [−3.1, −1.1]). TSI was not significantly different between conditions (p = .667). Word (1.6 ms, 95% CI [0.7, 2.5]) and color (1.3 ms, 95% CI [−0.2, 2.8]) completion times were longer (worse) for CALF compared to CON. In conclusion, calf raises decreased both cerebral perfusion and executive function. Simple strategies, such as fidgeting or calf raises, which have been reported to preserve vascular function in the legs, appear not to be sufficient to benefit cerebral perfusion or executive function.

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Section: Calf Blood Volumementioning

confidence: 99%

Effects of acute prolonged sitting on cerebral perfusion and executive function in young adults: A randomized cross‐over trial

et al. 2019

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“…4). [23][24][25][26] Many studies have investigated the use of NIRS to reveal the pathophysiology of patients with OI.27-31 NIRS offers an alternative solution for understanding the effects of a dysregulated autonomic nervous system on the delivery of blood to the brain. In addition, NIRS can potentially be used to monitor patients with inconclusive blood-pressure or heart-rate readings.…”

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confidence: 99%

“…4). [23][24][25][26] Many studies have investigated the use of NIRS to reveal the pathophysiology of patients with OI.…”

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confidence: 99%

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Application of near-infrared spectroscopy in clinical neurology

Kim

Bae

2018

Ann Clin Neurophysiol

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Near-infrared spectroscopy (NIRS) monitoring has been used mainly to detect reduced perfusion of the brain during orthostatic stress in order to assess orthostatic intolerance (OI). Many studies have investigated the use of NIRS to reveal the pathophysiology of patients with OI. Research using NIRS in other neurological diseases (e.g., stroke, epilepsy, and migraine) is continuing. NIRS may play an important role in monitoring the regional distribution of the hemodynamic flow in real time and thereby reveal the underlying pathophysiology and facilitate the management of not only patients with OI symptoms but also those with various neurological diseases.Key words: Orthostatic intolerance; Near-infrared spectroscopy; Clinical neurology INTRODUCTIONMany studies have investigated the hemodynamics and functions of the brain in various fields.1 Several noninvasive methods have been introduced in recent decades for measuring neuronal activity in the brain. 2 Neurophysiological techniques such as electroencephalography, magnetoencephalography, and event-related potentials offer the ability to measure overall changes in the electromagnetic field with an excellent time resolution, but these methods have poor spatial resolution. On the other hand, brain imaging techniques such as positron-emission tomography (PET) and functional magnetic resonance imaging (fMRI) have greatly increased our knowledge about neural circuitry. However, PET is highly sensitive to motion artifacts, confines the patient, and involves the injection of radioactive materials. Although fMRI is noninvasive and has excellent spatial resolution, it is expensive, highly sensitive to motion artifacts, and difficult to integrate with other imaging modalities. 3,4 Near-infrared spectroscopy (NIRS) was introduced as a new neuroimaging modality for Principle of NIRSNIRS is a noninvasive optical imaging tool for observing changes in the hemodynamics in the prefrontal area that is based on measuring the concentrations of HbO and HbR in the blood. Since Franz Jöbsis first studied the oxygenation of living tissues, NIRS has been extensively applied in imaging studies of brain activation. 6 The physiological activation of neurons leads to an imbalance between oxygen supply and utilization, increasing the concentration of HbO and decreasing the concentration of HbR. Most tissues are relatively transparent to light in the near-infrared range from 700 to 900 nm, and photons interact with tissues via absorption and scattering. This means that near-infrared light is less absorbed and scattered by tissue than is light at other wavelengths. 7 This range of wavelengths is often called an optical window since the light can easily pass through most tissues; however, it is reflected by HbO and HbR, and hence the absorption and scattering of light used for NIRS can provide information relevant to neural activity. 8 This light penetrates several centimeters through tissue and can still be detected (Fig. 1). The NIRS system consists of a light source and a photodetector. The l...

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“…The present findings indicate that postural change might have a significant impact on the ability of XCEL to measure central and lower‐limb PWV accurately and precisely. During orthostasis there is a propensity for blood to pool in the subdiaphragmatic venous system (Stone, Fryer, Ryan, & Stoner, ). This is likely to have occurred in the present study, as indicated by the reduction in SV, CO and Pb (Stoner et al., ).…”

Section: Discussionmentioning

confidence: 99%

Validity and reliability of lower‐limb pulse‐wave velocity assessments using an oscillometric technique

Stone

Fryer

Kelsch

et al. 2019

Experimental Physiology

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New Findings What is the central question of this study?There is growing interest in the effects of sedentarism on central and peripheral cardiovascular health. To permit further investigation, including larger epidemiological studies, there is a need to identify arterial health assessment tools that are valid (accurate) and reliable (precise), yet practical. What is the main finding and its importance?Lower‐limb vascular health (femoral–ankle pulse‐wave velocity) can be determined in a supine position with accuracy and precision using an oscillometrically based device. This technology might help to improve our understanding of the pathological mechanisms linking cardiovascular disease to sedentarism, including the interaction between peripheral and central vasculature. Abstract There is a growing interest in the deleterious effects of sedentary behaviour on lower‐limb arterial health. To permit further investigation, including larger epidemiological studies, there is a need to identify lower‐limb arterial health assessment tools that are valid and reliable, yet simple to administer. In this study, we sought to determine the validity and between‐day reliability of femoral–ankle pulse‐wave velocity (faPWV) measures obtained using an oscillometrically based device (SphygmocCor XCEL) in supine and seated positions. Doppler ultrasound was used as the criterion. A total of 47 healthy adults were recruited for validity (n = 32) and reliability (n = 15) analyses. Validity was determined by measuring faPWV in seated and supine positions using the XCEL and Doppler ultrasound devices, in a randomized order. Between‐day reliability was determined by measuring seated and supine faPWV using the XCEL on three different mornings, separated by a maximum of 7 days. The validity criterion [absolute standard error of estimate (aSEE) < 1.0 m s−1] was met in the supine [aSEE = 0.8 m s−1, 95% confidence interval (CI) 0.4–1.0], but not in the seated (aSEE = 1.2 m s−1, 95% CI 1.1–1.2) position. Intraclass correlation coefficient (ICC) estimates revealed that the XCEL demonstrated good reliability in the supine position (ICC = 0.83, 95% CI 0.65–0.93), but poor reliability in the seated position (ICC = 0.29, 95% CI 0.23–0.63). The oscillometric XCEL device can be used to determine lower‐limb pulse‐wave velocity with acceptable validity and reliability in the conventionally recommended supine position, but not in the seated position.

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The validity and reliability of continuous-wave near-infrared spectroscopy for the assessment of leg blood volume during an orthostatic challenge

Cited by 37 publications

References 28 publications

Effects of acute prolonged sitting on cerebral perfusion and executive function in young adults: A randomized cross‐over trial

Effects of acute prolonged sitting on cerebral perfusion and executive function in young adults: A randomized cross‐over trial

Application of near-infrared spectroscopy in clinical neurology

Validity and reliability of lower‐limb pulse‐wave velocity assessments using an oscillometric technique

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