The Chinese Time-honored Catering Brands (CTCBs) in the five northwestern provinces are the accumulation of culture in the northwest of China and have precious value. Their formation and development process have their own characteristics and rules. In order to clarify the spatial distribution characteristics and influencing factors of CTCBs in these provinces, this study uses geolocated social media data (the data of the CTCBs’ directory, location, and per capita consumption level), and applies statistical analysis, kernel density analysis, standard deviational ellipse, and buffer analysis to analyze the spatial distribution characteristics and influencing factors of CTCBs in the five northwestern provinces. The results show that: (1) the spatial development intensity of CTCBs is relatively strong in their original place, and their spatial distribution is uneven. The overall distribution is in the northwest-southeast direction, with strong agglomeration, and tends to be scattered in the periphery of the agglomeration area. There are some areas with higher concentrations distributed in the form of patches. (2) The number and spatial distribution of old brands with different grades and tastes have different characteristics. (3) The spatial distribution pattern of CTCBs is formed under a variety of factors, such as historical and traditional culture, regional traffic conditions and urban development patterns, etc.