The Value of Diffusion-Weighted Imaging in Combination With Conventional Magnetic Resonance Imaging for Improving Tumor Detection for Early Cervical Carcinoma Treated With Fertility-Sparing Surgery

Abstract

The addition of DWI to conventional MRI considerably improves the sensitivity and accuracy of tumor detection in young patients treated with fertility-sparing surgery, which supports the inclusion quantitative analysis of ADC value in routine MRI protocol before fertility-sparing surgery.

Rising Mortality Rate of Cervical Cancer in Younger Women in Urban China

“…3 Cervical cancer is one of the most preventable forms of cancer. There has also been significant improvement in screening, 4-8 diagnosis, [9][10][11] treatment, [12][13][14][15] and even chemoprevention [16][17][18] for cervical cancer. In the past decade, much effort has been made in China to reduce the burden of cervical cancer.…”

Assessment of parametrial invasion of cervical carcinoma, the role of T2-weighted MRI and diffusion weighted imaging with or without fusion

“…25e28 DWI could be useful to identify "low-risk" patients as the negative predictive value is high: 96e98% in the present study. 29,30 The present study has some limitations. First, the study was powered to assess a difference in AUC of 0.10 between conventional and fusion imaging with a prevalence of parametrial invasion of 15e25%.…”

Imaging of cervical cancer. Consensus of experts

“…Комментарий: предпочтительны 2D-Т2ВИ [17,27]. Для Т2ВИ в плоскости, перпендикулярной цервикальному каналу, толщина среза должна быть <4 мм, размер вокселя не более 1 × 1 × 4 мм, FOV не более 180 мм, подавление сигнала от жировой ткани не рекомендуется.…”

“…Сопоставление Т2ВИ с ДВИ опти мизирует оценку границ опухоли с окружающими тканями при измерении размера и распространенности опухоли в краниокаудальном направлении и при оценке параметральной инвазии (рис. 2) [27,41,42].…”