2021
DOI: 10.1097/md.0000000000024728
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The value of endobronchial ultrasound-guided transbronchial needle aspiration, 18-fluorodeoxyglucose positron emission tomography/computed tomography, and ultrasonography imaging techniques in the diagnosis of mediastinal and/or hilar malignant, anthracotic, and other benign lymph nodes

Abstract: Introduction: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a simple, reliable, minimally invasive and effective procedure. However, a surgical technique may be required, if the results are negative. Therefore, there is a need for new studies to increase the diagnostic value of EBUS-TBNA and provide additional information to guide the biopsy in performing the procedure. Here, we aimed to investigate the diagnostic value of EBUS-TBNA and 18-fluorodeoxyglucose positr… Show more

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Cited by 4 publications
(12 citation statements)
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“…In addition, the distribution of PET avid LNs was bilateral in 90% of the cases in our case series. The absolute number and distribution of PET avid LNs was not well characterized in other case series (7,8,13). In summary, key radiographic features that may differentiate lymph nodes with BAL from lymph nodes with metastatic disease include the smaller size and symmetric bilateral © Journal of Thoracic Disease.…”
Section: B a B Amentioning
confidence: 85%
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“…In addition, the distribution of PET avid LNs was bilateral in 90% of the cases in our case series. The absolute number and distribution of PET avid LNs was not well characterized in other case series (7,8,13). In summary, key radiographic features that may differentiate lymph nodes with BAL from lymph nodes with metastatic disease include the smaller size and symmetric bilateral © Journal of Thoracic Disease.…”
Section: B a B Amentioning
confidence: 85%
“…EBUS-TBNA identified BAL as an alternative explanation for the FDG avidity of all of these LNs (Table 3, Figure 1). In four of six patients, surgical resection of the primary lung cancer was performed (7,8,13). Other demographic findings, including mean age, duration of tobacco exposure and male predominance in our study are similar to prior studies.…”
Section: Resultsmentioning
confidence: 99%
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“…However, several benign pathological conditions including tuberculosis, sarcoidosis, reactive lymphadenopathies and anthracosis can mimic malignancy in terms of 18 F-FDG avidity at these sites. [96][97][98] The risk of malignancy on PET imaging appears to increase with nodal size (>2 cm), irregular contours and heterogeneous density, 99 unilateral accumulation of 18 F-FDG 100 and high standardised uptake value (SUV). The exact SUV cut-off for determining the risk of malignancy ranges between 4.5 and 6.48.…”
Section: Commentsmentioning
confidence: 99%
“…The exact SUV cut-off for determining the risk of malignancy ranges between 4.5 and 6.48. 97,99,101 In controversial cases, a tissue biopsy is recommended to establish a definitive diagnosis. 96,102,103 Histological and immuno-histological findings in our patient revealed anthracosis (Figure 3).…”
Section: Commentsmentioning
confidence: 99%