The Value of Heredity in the Detection and Study of Glaucoma*

Chronic open angle glaucoma: patient awareness of the nature of the disease, topical medication, compliance and the prevalence of systemic symptoms

“…A positive family history is a risk factor for development of COAG and has been reported in 13–25% of patients with COAG (Kellerman and Posner, 1955; Becker et al. , 1960; Leske et al.…”

“…A positive family history is a risk factor for development of COAG and has been reported in 13-25% of patients with COAG (Kellerman and Posner, 1955;Becker et al, 1960;Leske et al, 1995). However, the findings, of the Glaucoma Inheritance Study of Tasmania (GIST) suggest that a higher percentage of adult COAG may be inherited than hitherto reported (McNaught et al, 2000).…”

Quantification of Glaucomatous Field Defect in Primary Open Angle Glaucoma Patients at the time of Presentation: A Retrospective CrossSectional Study

“…Kellerman et al reporting 13-25% of patients having a 1st-degree relative with the same disease. [6] 23.33% of the patients in our study had a family history. This underlines the magnitude of the problem, where despite positive family history and possible knowledge about the disease, the patients tend to present late in the disease.…”

2. Primary Open-Angle Glaucoma

“…Mean IOPs of all groups increased with age, and there was positive correlation with systemic blood pressure.A family history of glaucoma should always raise a red flag. Such a history may be found in 13 to 25% of glaucoma patients 78. Both autosomal-recessive and -dominant transmission may be involved.…”