The value of mass screening for chlamydia control in high prevalence communities

Hodgins, Stephen; Rw, Peeling; Dery, Samuel; Bernier, F; LaBrecque, A; Jf, Proulx; Joly, J; Alary, Michel; Mabey, David

doi:10.1136/sti.78.suppl_1.i64

Cited by 17 publications

(28 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The prevalence in this study of 5.4% in UL and 6.3% in OPD (overall 5.9%) is on a par with a Danish study (5.8%), 15 higher than UK studies (1.2% 16 to 2.2% 17 18 ) though lower than a Canadian one (8%). 19 It should be noted that in the above studies with the exception of one, 17 participants were recruited from registers and specimens were ''home mailed.'' In this study all men were recruited on site.…”

Section: Discussionmentioning

confidence: 99%

Chlamydia trachomatis prevalence in men in the mid-west of Ireland

Powell

O’Connor²,

O'hlarlaithe³

et al. 2004

Sexually Transmitted Infections

View full text Add to dashboard Cite

Objectives: To estimate the prevalence of chlamydia infection in young men in the Mid-Western Health Board Region of Ireland, and to determine risk factors for its acquisition. Methods: Consecutive men attending orthopaedic clinics (OPD), and a university sports arena (UL) were recruited to a chlamydia prevalence study. All men aged 17-35 who had been sexually active and had not passed urine in the last hour were eligible. Information about chlamydia was given, informed consent obtained, and a self administered questionnaire was completed. A first void urine (FVU) was collected and tested by ligase chain reaction (LCR). Results: 82% (207/252) of men from OPD, and 60% (186/310) from UL participated. 6.3% (13/207) from the OPD and 5.4% (10/186) from UL tested LCR positive, giving an overall prevalence of 5.9% (23/ 393). Proved risk factors for chlamydial positivity were: (1) more than one sexual partner in previous 6 months, (2) more than eight lifetime sexual partners, (3) current symptoms (dysuria or discharge). No statistical significance was found for age, condom use, smoking, days since last sexual intercourse and previous GUM clinic attendance. No statistically significant difference to cost effective prevalence of 6% was shown. Conclusions: A 5.9% prevalence of Chlamydia trachomatis was found which is cost effective to screen and treat. Non-invasive screening of men in the community was possible. Numbers of sexual partners and current symptoms were significant risk factors. Since only 25% of men in this laboratory were diagnosed with chlamydia outside the GUM clinic, compared with 59% of women, it is important that community screening of men is promoted.H ealthcare providers often see chlamydial infection, like other STDs, as a women's health issue, as its complications in women are well known. As a result, men are relatively ignorant about its transmission, prevention, and control.1 No doubt this is partially because 50%-70% of infections in women 2 and 40%-50% of those in men 3 are clinically silent. Research in the United States and Sweden has shown that detection and treatment of asymptomatic infections in women result in a reduction of complications. 5The number of diagnoses of chlamydia has been consistently higher in women than men, by more than 30%. 6 In the Limerick regional laboratory in the 12 months up to October 2003, almost twice as many women (264/3851) as men (149/ 1496) were diagnosed positive. Over 75% of chlamydia positive men (112/149) were patients in the GUM clinic, compared to 41% of women (109/264). Screening men for chlamydial infection, especially those without symptoms has been considered problematic, 1 mainly because men are less likely than women to attend healthcare settings. 7 In the past, screening asymptomatic men was further hampered by the necessity for invasive sampling techniques.

show abstract

Section: Discussionmentioning

confidence: 99%

Chlamydia trachomatis prevalence in men in the mid-west of Ireland

Powell

O’Connor²,

O'hlarlaithe³

et al. 2004

Sexually Transmitted Infections

View full text Add to dashboard Cite

show abstract

“…18,43 Op beide studies zijn methodologische bezwaren geuit. 38 Onlangs heeft zich in Zweden een 'natuurlijk experiment' voorgedaan.…”

Section: Rct'sunclassified

Screening op urogenitale Chlamydia trachomatis-infecties: de stand van zaken

Bergen¹

2009

BIJB

View full text Add to dashboard Cite

SamenvattingInfectie met Chlamydia trachomatis (CT) is de meest frequent voorkomende bacteriële soa in Nederland. CT-infecties zijn een belangrijke oorzaak van ontstekingen in het kleine bekken, infertiliteit, buitenbaarmoederlijke zwangerschap en chronische buikpijn bij vrouwen. Zeventig procent van de infecties bij vrouwen en 50% bij mannen verloopt zonder specifieke symptomen. Huidige testmethoden middels amplificatietechnieken maken een screeningsprogramma via thuis verzamelde monsters mogelijk. In 2008 is gestart met een proefimplementatie om meer inzicht te krijgen in haalbaarheid, effectiviteit en impact.Kernpunten 1 Naar schatting vinden jaarlijks 60.000Chlamydia-infecties plaats in Nederland. 2 Actieve opsporing en vroege behandeling leveren voordelen op voor het individu (voorkómen van complicaties) en voor de volksgezondheid (voorkómen van verdere verspreiding). 3 Onderzoek van (thuis) zelf afgenomen monsters is betrouwbaar en maakt screening mogelijk zonder noodzaak tot lichamelijk onderzoek. 4 In 2008 is gestart met een proefimplementatie van Chlamydia-screening in Amsterdam, Rotterdam en Zuid-Limburg. 5 De bewijskracht voor effectiviteit en impact van een nationaal screeningsprogramma moet nog worden uitgebreid alvorens landelijke toepassing kan plaatsvinden.

show abstract

“…All non-EU studies performed appropriate analyses and five did not provide confidence intervals or raw numbers to calculate them from [87,104,105,106,107].…”

Section: Risk Of Bias In Included Studiesmentioning

confidence: 99%

“…There were four population-based studies that included a nationally representative sample of the general adult or adolescent population in Croatia (1 study, 1 publication [81]) and the USA (3 studies, 15 publications [83][84][85][86][87][88][89][90][91][92][93][94][95][96][97]). The remaining studies enrolled participants from the general population in one or more regions of a country (four studies in Australia, 6 publications [98][99][100][101][102][103], two studies in Canada, two publications [104,105], two studies in the USA, three publications [106][107][108]), or from a specific group within the general population (e.g. low income women in the USA [109,110], school students in New Zealand [111,112] or men presenting for military service in Switzerland [82]).…”

Section: Description Of Included Studiesmentioning

confidence: 99%

Opportunistic testing for urogenital infection with Chlamydia trachomatis in south-western Switzerland, 2012: a feasibility study

et al. 2015

View full text Add to dashboard Cite

The feasibility of opportunistic screening of urogenital infections with Chlamydia trachomatis was assessed in a cross-sectional study in 2012, in two cantons of south-western Switzerland: Vaud and Valais. Sexually active persons younger than?30 years, not tested for C. trachomatis in the last three months, were invited for free C. trachomatis testing by PCR in urine or self-applied vaginal swabs. Of 2,461 consenting participants, 1,899 (77%) were women and all but six (0.3%) submitted a sample. Forty-seven per cent of female and 25% of male participants were?younger than?20 years. Overall, 134 (5.5%) of 2,455 tested participants had a positive result and were followed up. Seven per cent of all candidates for screening were not invited, 10% of invited candidates were not eligible, 15% of the eligible candidates declined participation, 5% of tested participants testing positive were not treated, 29% of those treated were not retested after six months and 9% of those retested were positive for C. trachomatis. Opportunistic C. trachomatis testing proved technically feasible and acceptable, at least if free of charge. Men and peripheral rural regions were more difficult to reach. Efforts to increase testing and decrease dropout at all stages of the screening procedure are necessary.

show abstract

The value of mass screening for chlamydia control in high prevalence communities

Cited by 17 publications

References 7 publications

Chlamydia trachomatis prevalence in men in the mid-west of Ireland

Chlamydia trachomatis prevalence in men in the mid-west of Ireland

Screening op urogenitale Chlamydia trachomatis-infecties: de stand van zaken

Opportunistic testing for urogenital infection with Chlamydia trachomatis in south-western Switzerland, 2012: a feasibility study

Contact Info

Product

Resources

About