The Value of Neutrophil/Lymphocyte Ratio Combined with Red Blood Cell Distribution Width in Evaluating the Prognosis of Emergency Patients with Sepsis

Lin, Maosheng; Zhang, Louwei; Tang, Xuhua; Tang, Yejiang

doi:10.1155/2022/1673572

Cited by 3 publications

(3 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Finally, in our study, the morphological parameter of red blood cells, RDW, also proved to be an early independent predictor of sepsis risk in ICU patients. It has already been established that there is a correlation between the onset and development of sepsis and the level of RDW, which is an important predictor of death in patients with sepsis [24,25], and is closely related to inflammatory markers such as CRP. It has been postulated that inflammation may impair the maturation process of red blood cells, leading to accelerated entry of immature erythrocytes into the circulation [40].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The Role of New Morphological Parameters Provided by the BC 6800 Plus Analyzer in the Early Diagnosis of Sepsis

Sacchetti,

Vidali,

Esposito

et al. 2024

Diagnostics

View full text Add to dashboard Cite

Background: Late diagnosis of sepsis is associated with adverse consequences and high mortality rate. The aim of this study was to evaluate the diagnostic value of hematologic research parameters, that reflect the cell morphology of blood cells, available on the BC 6800 plus automated analyzer (Mindray) for the early detection of sepsis. Materials and Methods: A complete blood count (CBC) was performed by Mindray BC 6800 Plus Analyzer in 327 patients (223 with a confirmed diagnosis of sepsis following sepsis-3 criteria, 104 without sepsis), admitted at the Intensive Care Unit of the Novara’s Hospital (Italy) and in 56 patients with localized infection. Results: In univariate logistic regression, age, Hb, RDW, MO#, NMR, NeuX, NeuY, NeuZ, LymX, MonX, MonY, MonZ were associated with sepsis (p < 0.005). In multivariate analysis, only RDW, NeuX, NeuY, NeuZ, MonX and MonZ were found to be independent predictors of sepsis (p < 0.005). Morphological research parameters are confirmed to be predictors of sepsis even when analyzing the group with localized infection. Conclusions: In addition to already established biomarkers and basic CBC parameters, new morphological cell parameters can be a valuable aid in the early diagnosis of sepsis at no additional cost.

show abstract

Section: Discussionmentioning

confidence: 99%

“…The Neutrophil-to-Monocyte Ratio (NMR), Lymphocyte-to-Monocyte Ratio (LMR), and Red Blood Cell Distribution Width (RDW) were also examined as prognostic markers for adverse outcomes in sepsis and as predictors of bacterial infection [22][23][24][25].…”

Section: Data Collectionmentioning

confidence: 99%

The Role of New Morphological Parameters Provided by the BC 6800 Plus Analyzer in the Early Diagnosis of Sepsis

Sacchetti,

Vidali,

Esposito

et al. 2024

Diagnostics

View full text Add to dashboard Cite

show abstract

“…Patients with COVID-19 with severe disease had significantly higher absolute neutrophil counts. 17 Sinurat et al 18 mention the distinct number of meaningful neutrophils in COVID-19 degrees, mild, moderate, and severe. That is illustrated by the higher number of neutrophils in severe groups than those of mild degrees (4.3 vs 3.2 x 10 9 /L).…”

Section: Neutrophil Count and Mortalitymentioning

confidence: 99%

The Effect of C-Reactive Protein Levels, Neutrophil, and Lymphocyte Count to Mortality of COVID-19 Patients with Sepsis in Referral Hospital

Malikhah,

Dhani Redhono Harioputro,

Agung Susanto

et al. 2024

IJTID

View full text Add to dashboard Cite

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by infection of Severe Acute RespiratoryDistress Syndrom Coronavirus-2 (SARS CoV-2). COVID-19 patients may develop sepsis, the disregulation ofthe immune system that causes organ dysfunction and life-threatening situations. High mortality of COVID-19and sepsis make it important to study. The purpose of this study is to analyze the effect of CRP levels, neutrophil,and lymphocyte count to mortality of COVID-19 patients with sepsis. This study is an analytic observational studywith a cross-sectional approach. Samples were randomly retrieved of COVID-19 patients with sepsis admittedin referral hospital. Univariate, bivariate, and multivariate analysis used SPSS 26th version of Windows. Theresults of this study indicate a significant effect of CRP levels and neutrophil count on mortality of COVID-19patients with sepsis. Meanwhile, lymphocyte count had no significant effects. The multivariate analysis showedits significance value. Partially, the effect of neutrophils on the patient's mortality has a significant value. Theconclusion of this study is CRP levels and neutrophil count simultaneously have an effect on higher mortality ofCOVID-19 patients with sepsis.

show abstract

The Role of New Morphological Parameters Provided by the BC 6800 Plus Analyzer in the Early Diagnosis of Sepsis

Sacchetti,

Vidali,

Esposito

et al. 2024

Preprint

View full text Add to dashboard Cite

Background and Aims: Late diagnosis of sepsis is associated with adverse consequences and high mortality rate. The aim of this study was to evaluate the diagnostic value of hematologic research parameters, that reflect the cell morphology of blood cells, available on the BC 6800 plus automated analyzer (Mindray) for the early detection of sepsis. Materials and Methods: A complete blood count (CBC) was performed by Mindray BC 6800 Plus Analyzer in 327 patients (223 with a confirmed diagnosis of sepsis following sepsis-3 criteria, 104 without sepsis), admitted at the Intensive Care Unit of the Novara’s Hospital (Italy) and in 56 patients with localized infection. Results: In univariate logistic regression, age, Hb, RDW, MO#, NMR, NeuX, NeuY, NeuZ, LymX, MonX, MonY, MonZ were associated with sepsis (p<0.005). In multivariate analysis, only RDW, NeuX, NeuY, NeuZ, MonX and MonZ were found to be independent predictors of sepsis (p<0.005). Morphological research parameters are confirmed to be predictors of sepsis even when analyzing the group with localized infection. Conclusions: In addition to already established biomarkers and basic CBC parameters, new morphological cell parameters can be a valuable aid in the early diagnosis of sepsis at no additional cost.

show abstract

The Value of Neutrophil/Lymphocyte Ratio Combined with Red Blood Cell Distribution Width in Evaluating the Prognosis of Emergency Patients with Sepsis

Cited by 3 publications

References 20 publications

The Role of New Morphological Parameters Provided by the BC 6800 Plus Analyzer in the Early Diagnosis of Sepsis

The Role of New Morphological Parameters Provided by the BC 6800 Plus Analyzer in the Early Diagnosis of Sepsis

The Effect of C-Reactive Protein Levels, Neutrophil, and Lymphocyte Count to Mortality of COVID-19 Patients with Sepsis in Referral Hospital

The Role of New Morphological Parameters Provided by the BC 6800 Plus Analyzer in the Early Diagnosis of Sepsis

Contact Info

Product

Resources

About