The value of radionuclide bone imaging in selected patients with osteogenic sarcoma metastatic to lung

Abstract

Bone scintigraphic findings are presented in three pediatric patients with osteogenic sarcoma metastatic to lung. The bone imaging radionuclide was concentrated to a variable degree within the pulmonary metastases. Radionuclide bone imaging was valuable in confirming the presence of metastatic disease to lung in two patients and diagnosing previously unsuspected pulmonary metastatic disease in one patient.

Role of Radionuclide Studies in Paediatric Orthopaedic Practice: A Review

“…Extraosseous localization of TcMDP may be seen in lung, liver and soft tissue deposits in Ewing's sarcoma, osteosarcoma, round cell tumours and in neuroblastoma (Young & L'Heureaux 1978, Siddiqui et al 1979, Kirks et al 1980. It is also seen in the primary tumour in all calcified neuroblastomas and about half the non-calcified lesions, and can thus provide a positive diagnosis while awaiting vanillylmandelic acid (VMA) results (Smith et al 1980b, Murray & Greensmith 1978.…”