The Value of T1 Mapping Techniques in the Assessment of Myocardial Interstitial Fibrosis

SAturation‐recovery and Variable‐flip‐Angle–based three‐dimensional free‐breathing cardiovascular magnetic resonance T1 mapping at 3 T

“…Two‐dimensional (2D) myocardial T 1 mapping, such as modified Look‐Locker inversion recovery (MOLLI) 5 and saturation‐recovery single‐shot acquisition (SASHA), 6 is now widely used in clinical practice. Generally, T 1 of three to five left‐ventricle (LV) slices is measured by multiple breath‐holding scans, which may be sufficient for detecting the global change (e.g., diffuse fibrosis, 7 iron overload 8 ). However, T 1 of limited slices is incomplete in detection of the regional and focal heterogeneity (e.g., infarction 9 and scar 10 ).…”

O Desafio de Tornar a Ressonância Cardíaca uma Realidade Global

“…Nos últimos anos presenciamos uma avalanche de artigos científicos de ressonância cardíaca sobre a utilidade dos mapas paramétricos, seja no acometimento cardíaco precoce de diferentes patologias ou no diagnóstico etiológico específico, especialmente do Mapa T1 no diagnóstico diferencial de fenótipos hipertróficos como a Amiloidose Cardíaca ou a Doença de Anderson Fabry. 16 - 18 No entanto, essas técnicas requerem software avançado, bem como tempo significativo para adquirir dados pré e pós-contraste, e o uso desta tecnologia em países em desenvolvimento é caro e consome tempo de aquisição e pós-processamento.…”

“…In recent years, we have witnessed an avalanche of scientific articles on cardiac resonance imaging on the usefulness of parametric maps, either in the early cardiac involvement of different pathologies or in the specific etiological diagnosis, especially the T1 Map in the differential diagnosis of hypertrophic phenotypes such as Cardiac Amyloidosis or by Anderson Fabry. 16 , 18 However, these techniques require advanced software and significant time to acquire pre- and post-contrast data, and using this technology in developing countries is expensive and time-consuming acquisition and post-processing.…”