The Valve of the Foramen Ovale its Relation to Pulmonary Vein Entries

Franklin, K. J.; Amoroso, E. C.; Barclay, A. E.; Prichard, Marjorie M. L.

doi:10.1016/s0372-5545(17)34004-x

Cited by 6 publications

(15 citation statements)

References 7 publications

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“…In postnatal mouse and rat hearts, there is a fairly extensive primary septum as compared to the fossa ovalis, at least in contracted atria, and the foramen ovale is closed within the first week after birth (Cole‐Jeffrey et al, ; Elliott et al, ). Possibly, the secondary foramen is relatively small in rodents, but the configuration in rodents (order Rodentia) resembles those of human and other primates (Franklin et al ., ; Anderson et al, ). In carnivores (order Carnivora), there is a single large secondary foramen, but this may come at the end of a short sleeve‐like extension of the primary septum, which projects into the left atrial lumen (Franklin et al ., ; Macdonald et al, ; Macdonald and Johnstone, ).…”

Section: Normal Development Of the Atrial Septum In Eutherian Mammalsmentioning

confidence: 98%

“…B). Most of the left atrial face of the septum is the primary septum, commonly called the “flap valve” in medical literature, which has two horns, or cornua (Franklin et al ., ), extending cranially (Jensen et al, ). Between the horns is a depression that is the postnatal remnant of the embryonic secondary foramen, which is probe patent in the human heart as shown in Figure B.…”

Section: The Anatomy Of the Atrial Septum Of Eutherian Mammalsmentioning

confidence: 99%

“…Extending back to at least the 19th century, it was occasionally observed that the fossa ovalis can be found in eutherian mammals only, and not in marsupial mammals, such as kangaroos, or monotreme mammals (Martin, ; Röse, ; Franklin et al ., ; Ottaway, ; Rowlatt, ; Runciman et al, ). Developmental studies further showed that the secondary foramen is particular to eutherian mammals (Röse, ; Franklin et al ., ). In marsupials, for instance, the primary septum does develop secondary perforations, but these will not coalesce to a secondary foramen.…”

Section: The Anatomy Of the Atrial Septum Of Eutherian Mammalsmentioning

confidence: 99%

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Evolution and Development of the Atrial Septum

Jensen

Wang

Moorman

2018

The Anatomical Record

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The complete division of the atrial cavity by a septum, resulting in a left and right atrium, is found in many amphibians and all amniotes (reptiles, birds, and mammals). Surprisingly, it is only in eutherian, or placental, mammals that full atrial septation necessitates addition from a second septum. The high incidence of incomplete closure of the atrial septum in human, so‐called probe patency, suggests this manner of closure is inefficient. We review the evolution and development of the atrial septum to understand the peculiar means of forming the atrial septum in eutherian mammals. The most primitive atrial septum is found in lungfishes and comprises a myocardial component with a mesenchymal cap on its leading edge, reminiscent to the primary atrial septum of embryonic mammals before closure of the primary foramen. In reptiles, birds, and mammals, the primary foramen is closed by the mesenchymal tissues of the atrioventricular cushions, the dorsal mesenchymal protrusion, and the mesenchymal cap. These tissues are also found in lungfishes. The closure of the primary foramen is preceded by the development of secondary perforations in the septal myocardium. In all amniotes, with the exception of eutherian mammals, the secondary perforations do not coalesce to a secondary foramen. Instead, the secondary perforations persist and are sealed by myocardial and endocardial growth after birth or hatching. We suggest that the error‐prone secondary foramen allows large volumes of oxygen‐rich blood to reach the cardiac left side, needed to sustain the growth of the extraordinary large offspring that characterizes eutherian mammals. Anat Rec, 302:32–48, 2019. © 2018 The Authors. The Anatomical Record published by Wiley Periodicals, Inc. on behalf of American Association of Anatomists.

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Section: Normal Development Of the Atrial Septum In Eutherian Mammalsmentioning

confidence: 98%

Section: The Anatomy Of the Atrial Septum Of Eutherian Mammalsmentioning

confidence: 99%

Section: The Anatomy Of the Atrial Septum Of Eutherian Mammalsmentioning

confidence: 99%

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Evolution and Development of the Atrial Septum

Jensen

Wang

Moorman

2018

The Anatomical Record

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“…There are very few accounts of the anatomy of this cardiac structure in species other than man and several domestic animals (Mosca 1914;Franklin et al 1942;Barclay et al 1944;Macdonald et al 1988). Prior to the present study almost nothing appears to have been published on the subject with regard to seal fetuses, despite these animals having an interestingly different set of physiological challenges to face during development in utero (Hindell et al 1992;Fedak and Thompson 1993).…”

Section: Discussionmentioning

confidence: 99%

“…Accounts of the anatomy of the ducti venosus and arteriosus of the seal have been given earlier (Owen, 1831 ;Hepburn 1909;Haig 1914;Slijper, 1936Slijper, , 1961. However, although the gross structure of the foramen ovale of a number of domestic and other terrestrial mammals has been commented upon (Mosca 1914;Amoroso et al 1942;Franklin et al 1942;Macdonald 1988;Macdonald et al 1988), there are very few descriptions of this structure in aquatic mammals (Slijper 1961). There are brief reports relating to the foramen ovale of pinnipeds in the early literature, indicating that it had been given some attention.…”

Section: Introductionmentioning

confidence: 99%

Comparative anatomy of the cardiac foramen ovale in the Pinnipedia

Macdonald¹,

Dixon²,

Boyd³

1995

Can. J. Zool.

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The structure of the cardiac foramen ovale from eight genera of pinnipeds was studied using the scanning electron microscope. Specimens were obtained from fetuses or neonates of the Californian sea lion (Zalophus californianus), Antarctic fur seal (Arctocephalus gazella), walrus (Obenus rosmurus), grey seal (Halichoerus gryphus), ringed seal (Phoca hispida), bearded seal (Erignathus barbatus), Weddell seal (Leptonychotes weddelli), and crabeater seal (Lobodon carcinophagus). In each species, the structure that permits oxygenated blood from the placenta flowing in the caudal vena cava to pass directly into the left side of the heart, the foramen ovale, when viewed from the terminal part of the caudal vena cava had the appearance of the entrance to a short tunnel. A thin fold of tissue, the developed remains of the septum primum, projected from the caudal edge of the foramen ovale into the lumen of the left atrium. It constituted about 75% of the inner surface of the tunnel, and was generally unfenestrated. The wall of the interatrial septum contributed the "floor." The distal end of the tunnel was straight-edged. In most cases the septum primum was long enough to cover the foramen ovale. The siting of pulmonary veins in the roof of the left atrium appeared to be such that drainage from them after birth would press the septum primum over the foramen opening, thereby functionally closing it. Collapses of the tunnel was seen in all the neonatal seals, and in the 1-month-old neonate the fold of tissue was anchored to the interatrial septum along the surface of the crista dividens, which lay in the left atrium. Cellular protrusions and thread formation may play a role in the closure of the foramen ovale.RCsumC : La structure du foramen ovale a Ct C CtudiCe au microscope Clectronique h balayage chez huit genres de pinnipkdes. Les organes not Ct C prClevCs chez des fCtus ou des nouveau-nCs de l'Otarie de Californie (Zalophus californianus), de I'Otarie de Kerguelen (Arctocephalus gazella), du Morse (Odobenus rosmurus), du Phoque gris (Halichoerus gryphus), du Phoque annelC (Phoca hispida), du Phoque barbu (Erignathus barbatus), du Phoque de Weddell (Leptonychotes weddelli) et du Phoque crabier (Lobodon carcinophagus). Vu de la partie terminale de la veine cave postdrieure, le foramen ovale, structure qui permet au sang oxygCnC provenant du placenta par la veine cave de passer directement dans la partie gauche du coeur, a l'apparence de I'entrCe d'un tunnel court chez chacune des espkces. Un mince repli de tissu, vestige du septum primaire, est issu de la bordure caudale du trou et se prolonge jusque dans la lumittre de l'oreillette gauche. Ce repli constitue environ 75% de la surface interne du tunnel et ne comporte gCnCralement pas de pores; la paroi du septum interatrial constitue le N plancher ,,. Le bord distal du "tunnel" est droit. Dans la plupart des cas, le septum primaire est suffisamment long pour couvrir le foramen ovale. La position des veines pulmonaires dans le plafond de l'oreillette gauche permet de suppo...

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Evolutionary Aspects of Chamber Formation and Septation

Jensen,

Moorman

2024

Advances in Experimental Medicine and Biology

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The Valve of the Foramen Ovale its Relation to Pulmonary Vein Entries

Cited by 6 publications

References 7 publications

Evolution and Development of the Atrial Septum

Evolution and Development of the Atrial Septum

Comparative anatomy of the cardiac foramen ovale in the Pinnipedia

Evolutionary Aspects of Chamber Formation and Septation

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