The variability of fixation suppression of caloric-induced nystagmus

Schuchman, Gerald I.; Uri, Nechama

doi:10.1017/s0022215100100052

Cited by 4 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This test method does have some limitations and should not be over-estimated. Several studies on visual fixation suppression in healthy control subjects have shown a high inter- and intra-individual variability of measurement results 30 . In our patients, the specificity of this test as an indicator for post-operative vertigo was only moderate.…”

contrasting

confidence: 44%

Impaired fixation suppression is a risk factor for vertigo after cochlear implantation

et al. 2009

View full text Add to dashboard Cite

show abstract

contrasting

confidence: 44%

Impaired fixation suppression is a risk factor for vertigo after cochlear implantation

et al. 2009

View full text Add to dashboard Cite

show abstract

“…A high variability was also reported for the fixation suppression index of caloric-induced nystagmus. 15 One potential problem with OFI scores is the problem of dividing values through zero or values close to zero explaining this variability. OFI scores are derived from a normalization procedure and represent a relative proportion of nystagmus suppression.…”

Section: Discussionmentioning

confidence: 99%

Stroke Prediction Based on the Spontaneous Nystagmus Suppression Test in Dizzy Patients

et al. 2021

View full text Add to dashboard Cite

ObjectiveFailure of fixation suppression of spontaneous nystagmus is sometimes seen in patients with vestibular strokes involving the cerebellum or brainstem, however, the accuracy of this test for the discrimination between peripheral and central causes in patients with an acute vestibular syndrome (AVS) is unknown.MethodsPatients with AVS were screened and recruited (convenience sample) as part of a prospective cross-sectional study in the Emergency Department between 2015-2020. All patients received neuroimaging which served as a reference standard. We recorded fixation suppression with video-oculography (VOG) for straight, right and left gaze. The ocular fixation index (OFI) and the spontaneous nystagmus slow velocity reduction was calculated.ResultsWe screened 1646 dizzy patients in the emergency department and tested for spontaneous nystagmus in 148 included AVS patients. We analyzed 56 patients with a diagnosed acute unilateral vestibulopathy (vestibular neuritis) and 28 patients with a confirmed stroke. There was a complete nystagmus fixation suppression in 49.5% of AVS patients, in 40% of patients with vestibular neuritis and in 62.5% of vestibular strokes. OFI scores had no predictive value for detecting strokes, however, a nystagmus reduction of less than 2deg/s showed a high accuracy of 76.9% (CI 0.59-0.89) with a sensitivity of 62.2% and specificity of 84.8% in detecting strokes..ConclusionsThe presence of fixation suppression does not rule out a central lesion. The magnitude of suppression was lower compared to patients with vestibular neuritis. The nystagmus suppression test still predicts accurately vestibular strokes provided that eye movements are recorded with VOG.Classification of EvidenceThis study provides Class II evidence that in patients with an acute vestibular syndrome, decreased fixation suppression recorded with VOG occurred more often in stroke (76.9%) than in vestibular neuritis (37.8%).

show abstract

Effect of Temperature on Fixation Suppression Ability in Normal Subjects: The Need for Temperature-and Age-Dependent Normal Values

Jacobson

Henry²

1989

Ann Otol Rhinol Laryngol

View full text Add to dashboard Cite

The purpose of the present investigation was to determine whether temperature has an effect on the magnitude of fixation suppression (FS) in normal subjects. The subject population consisted of 23 patients ranging in age from 35 to 74 years (mean age of 58.13 years). Each subject received a conventional vestibulometric test battery that included bithermal caloric testing and the FS test. The warm caloric media elicited larger nystagmus slow-phase eye velocities than the cool caloric media. Following warm caloric irrigations, FS was significantly smaller than that following cool caloric irrigations. It also worsened as a function of subject age. The results suggest that separate normal upper limits for FS need to be determined for cool and warm caloric testing. They also suggest that FS ability may decrease with age.

show abstract

The variability of fixation suppression of caloric-induced nystagmus

Cited by 4 publications

References 14 publications

Impaired fixation suppression is a risk factor for vertigo after cochlear implantation

Impaired fixation suppression is a risk factor for vertigo after cochlear implantation

Stroke Prediction Based on the Spontaneous Nystagmus Suppression Test in Dizzy Patients

Effect of Temperature on Fixation Suppression Ability in Normal Subjects: The Need for Temperature-and Age-Dependent Normal Values

Contact Info

Product

Resources

About