The utility of employing elevated scores on the Depression and Psychasthenia scales of the Minnesota Multiphasic Personality Inventory, MMPI, as an indicator of a genuine, enduring clinical problem in need of remediation was investigated for a male college student population. The personal, academic, and occupational histories of entering students scoring above T = 60 on these scales, N = 54, were compared with those of a comparable random group over an 8% year period. Based on university records and self-report questionnaire data, the high scores exhibited, p < .05, greater difficulty with personal adjustment, in graduating from college, and in rinding a job and deciding on a career; they were earning lower salaries and fewer had married. Nearly half had sought professional help for an emotional problem. Pilot data further suggest that MMPI scale scores for this population decrease following psychotherapy but not with the passage of time alone.