The Veterans Administration Longitudinal Study of Oral Health and Disease

Kapur, Kanika; Glass, Robert L.; Loftus, Edward R.; Alman, John E.; Feller, Ralph P.

doi:10.2190/wll4-et76-uqwn-r5fl

Cited by 95 publications

(64 citation statements)

References 11 publications

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“…Beginning in 1961, the Normative Aging Study enrolled 2,280 medically healthy male volunteers, aged 25 to 84 yrs, from the Greater Boston area. A subset of 1,231 volunteers enrolled in the Dental Longitudinal Study beginning in 1969 (Kapur et al, 1972). Men were not Veterans Affairs patients and have gotten their medical and dental care in the private sector.…”

Section: Methodsmentioning

confidence: 99%

Retained Asymptomatic Third Molars and Risk for Second Molar Pathology

et al. 2013

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Prophylactic extraction of unerupted asymptomatic third molars is the most common oral surgery procedure in the United States. However, limited evidence exists to justify its costs and associated morbidity. We analyzed data collected over 25 years from 416 adult men enrolled in the Veterans Affairs Dental Longitudinal Study to evaluate the association of retained asymptomatic third molars with risk of adjacent second molar pathology (caries and/or periodontitis), based on third molar status (i.e., absent, erupted, or unerupted). Unerupted molars were further categorized as either "soft tissue" or "bony" impacted. We found that the lowest prevalence and incidence of second molar pathology occurred when the adjacent third molar was absent. The presence of a third molar that was soft tissue impacted increased the risk of incident second molar pathology 4.88-fold (95% confidence interval: 2.62, 9.08). Having an erupted or "bony" impacted third molar increased the risk of incident second molar pathology by 1.74 (95% confidence interval: 1.34, 2.25) and 2.16 (95% confidence interval: 1.56, 2.99), respectively. The retention of third molars is associated with increased risk of second molar pathology in middle-aged and older adult men.

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Section: Methodsmentioning

confidence: 99%

Retained Asymptomatic Third Molars and Risk for Second Molar Pathology

et al. 2013

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“…Participants were 893 white males in the Department of Veterans Affairs (VA) Dental Longitudinal Study, a closed-panel, observational cohort study of aging and oral health among healthy men (Kapur et al, 1972). Oral health, weight, medical health, and lifestyle were assessed at triennial dental and medical examinations.…”

Section: Materials and Methods Participantsmentioning

confidence: 99%

Changes in Body Weight and Adiposity Predict Periodontitis Progression in Men

et al. 2012

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“…15 The first DLS examination was used as the baseline for the present analyses. We excluded 12 men who had developed CHD before their first DLS examination.…”

Section: Study Populationmentioning

confidence: 99%

Age-Dependent Associations Between Chronic Periodontitis/Edentulism and Risk of Coronary Heart Disease

Dietrich

Jiménez²,

Kaye³

et al. 2008

Circulation

246

225

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Background-Several epidemiological studies have suggested periodontitis as a risk factor for coronary heart disease (CHD), but results have been inconsistent. Methods and Results-We evaluated the association between clinical and radiographic measures of periodontitis, edentulism, and incident CHD (angina, myocardial infarction, or fatal CHD) among 1203 men in the VA Normative Aging and Dental Longitudinal Studies who were followed up with triennial comprehensive medical and dental examinations up to 35 years (median 24 years). Cox proportional hazards models with time-varying effects of exposure and potential confounders were fit. We found a significant dose-dependent association between periodontitis and CHD incidence among men Ͻ60 years of age (hazard ratio 2.12, 95% confidence interval 1.26 to 3.60 comparing highest versus lowest category of radiographic bone loss, P for trendϭ0.02), independent of age, body mass index, smoking, alcohol intake, diabetes mellitus, fasting glucose, total cholesterol, high-density lipoprotein cholesterol, triglycerides, hypertension, systolic and diastolic blood pressure, education, marital status, income, and occupation. No association was found among men Ͼ60 years of age. Similar results were found when the sum of probing pocket depths was used as a measure of periodontitis. Among men Ն60 years of age, edentulous men tended to have a higher risk of CHD than dentate men in the lowest bone loss (hazard ratio 1.61, 95% confidence interval 0.95 to 2.73) and lowest pocket depth (hazard ratio 1.72, 95% confidence interval 1.03 to 2.85) categories, independent of confounders. Conclusions-Chronic periodontitis is associated with incidence of CHD among younger men, independent of established cardiovascular risk factors. (Circulation. 2008;117:1668-1674.)

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The Veterans Administration Longitudinal Study of Oral Health and Disease

Cited by 95 publications

References 11 publications

Retained Asymptomatic Third Molars and Risk for Second Molar Pathology

Retained Asymptomatic Third Molars and Risk for Second Molar Pathology

Changes in Body Weight and Adiposity Predict Periodontitis Progression in Men

Age-Dependent Associations Between Chronic Periodontitis/Edentulism and Risk of Coronary Heart Disease

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