In this study, free vibration and damping behavior of cylindrical sandwich panel with electro-rheological core and graphene platelets reinforced composite (GPLRC) facing sheets based on first-order shear deformation theory of thick cylindrical shells referred by Qatu (FSDTQ) is investigated. Effective material properties of graphene platelets reinforced composite are determined according to the Halpin–Tsai micromechanical model. The governing equations of motion with required boundary conditions are derived using Hamilton’s principle. Afterward, these equations are solved analytically using the Fourier series solution for simply-supported boundary conditions, and for the other edges boundary conditions, we used the generalized differential quadrature method. The exactness and correctness of the present formulation are validated by comparing the results with those of existing literature. Finally, the influences of various parameters such as the electric fields, geometrically parameters, boundary conditions, the volume fraction of GPL, and GPL distributions pattern on vibration behavior and modal loss factor is examined. According to the results, the influence of the GPL volume fraction and electric field on the frequencies and modal loss factor is significant. This achievement can help design intelligent controlling structures for various applications.