The benefits of nature-based solutions to address the climate and biodiversity challenges have become widely acknowledged. In numerous ways, nature-based solutions align with the Sustainable Development Goals. Serbia, like many other countries, faces many negative impacts of climate change crises. In order to meet sustainable development goals linked to water pollution and biodiversity, we investigated the potential of two plants, namely, Iris pseudocorus L. and Juncus effusus L., and tested for zinc reduction, previously found as an emerging contaminant of urban waters in Serbia. We focused on the investigation of native Serbian plants, that are reported as highly valuable and endangered. Results confirmed that both plant species have high accumulation capacity for Zn uptake, whereas growth and resistance were higher for Juncus effusus L. plants. While the concentration of zinc in Iris plants ranged from 45.85 mg/L to 193.05 mg/L, the concentration found in Juncus plants ranged from 36.2 mg/L to 264.59 mg/L for leaves and 53.20 mg/L for roots. This study contributes to the support for achieving the Sustainable Development Goals in Serbia within biodiversity conservation and sustainable water management, by providing information of plant species that can be included in future sustainable nature-based solutions projects, like bioretention systems and constructed wetlands.