The Waiting List Mortality of Pediatric Heart Transplantation Candidates in Korea before the Pediatric Ventricular Assist Device Era

Jeung, Min Sub; Kim, Mi Jin; Huh, June; Kang, I-Seok; Kim, Jun Seok; Yu, Jeong Jin; Song, Jinyoung

doi:10.3346/jkms.2021.36.e283

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…This process involves obtaining consent for donation and confirming brain death, along with matching the right blood type and meeting other criteria [ 2 , 14 ]. The worldwide shortage of suitable donor hearts leads to tragic outcomes, with adult waiting list mortality rates at 15% and paediatric rates ranging from 5% to 32% [ 15 , 16 ].…”

Section: Introductionsmentioning

confidence: 99%

Acceptance, Awareness, Attitude, and Practices toward Heart Transplantation: A Saudi Based Survey

Abukhudair,

Hafiz,

Alosaimi

et al. 2023

Journal of the Saudi Heart Association

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Introductions The awareness of brain death and heart donation (HD) among the Saudi population remains limited, coupled with negative attitudes toward heart donation, resulting in a significant gap between the demand for donor hearts and the available supply. This study aimed to comprehensively understand the current perceptions, attitudes, and practices of the Saudi population regarding HD, as well as identify the obstacles. The ultimate goal was to strengthen the local donor pool. Methods A cross-sectional study was conducted from March to May 2023, employing a self-administered internet survey. The survey collected demographic information, assessed awareness, attitudes, and practices related to HD, and was completed by 1820 participants from various regions in Saudi Arabia. Data was analyzed using SPSS version 25 (SPSS Inc., Chicago, Illinois, USA). Chi-square test, Independent-samples t-test, one way analysis of variance test (ANOVA) and Spearman correlation coefficient was performed with the significance level set at p < 0.05. Results A significant portion of the population (out of 1820 participants) lacked organ donation cards and were uncertain about the registration process. Participants displayed a moderate level of knowledge about HD, with roughly half holding unfavorable attitudes toward HD. A considerable percentage of participants 62.0% were unwilling to register as heart donors, but a majority (79.9%) were willing to contribute by disseminating information about HD. The study identified significant associations between knowledge scores and several factors, including age (p = 0.002), career (p = 0.000), possession of an organ donation card (p = 0.000), and a history of transplantation or organ donation among relatives (p = 0.000). A significant relationship was observed between attitude scores and several factors, including career (p = 0.001), Saudi region (p = 0.025), possession of an organ donation card (p = 0.000), and a history of transplantation or organ donation among relatives (p = 0.000). Conclusion The study highlights the urgent need for increased awareness to bolster the number of local heart donors. The involvement of healthcare professionals and social campaigns is essential to enhance public knowledge and potentially boost the willingness of individuals to become donors.

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Section: Introductionsmentioning

confidence: 99%

Acceptance, Awareness, Attitude, and Practices toward Heart Transplantation: A Saudi Based Survey

Abukhudair,

Hafiz,

Alosaimi

et al. 2023

Journal of the Saudi Heart Association

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Donor Characteristics and Outcomes of Pediatric Heart Transplantation in South Korea

Kim,

Shin,

et al. 2024

Pediatric Transplantation

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BackgroundHeart transplantation is often limited by the availability of transplantable donor heart and understanding of donor aspects that would influence transplant outcomes becomes important. In this study, donor characteristics and their impact on the outcomes of pediatric heart transplantations performed in South Korea were investigated.MethodsWe reviewed the medical records of patients less than 18 years old who received heart transplantation between 2002 and 2022 in three tertiary hospitals located in South Korea.ResultsA total of 139 cases were enrolled. One‐year mortality was 10.4% and total mortality was 33.8%. Forty‐nine recipients (35.3%) showed biopsy‐proven rejections and 20 (14.4%) showed cardiac allograft vasculopathy during mean follow‐up of 6.4 ± 4.9 years. Six recipients (4.5%) showed left ventricle ejection fraction of less than 55% post‐transplantation. The mean age of the donors was 23.0 ± 15.4 years. The most common cause of death of the donors was unspecified illness (46.4%). Donors with a history of diabetes, hypertension, smoking, and alcohol consumption were 0%, 3.1%, 32.1%, and 34.4%, respectively. Mean total ischemic time was 191.6 ± 72.7 min, while total ischemic time was over 4 h in 37 patients (26.6%). There were no significant relationship between donor factors and survival. However, donor's history of drinking or cardiopulmonary resuscitation was significantly associated with acute rejection and donor's age with cardiac allograft vasculopathy.ConclusionDonor factors did not show significant impact on post‐transplant survival but some factors were predictive of post‐transplant rejection and cardiac allograft vasculopathy.

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The Waiting List Mortality of Pediatric Heart Transplantation Candidates in Korea before the Pediatric Ventricular Assist Device Era

Cited by 2 publications

References 15 publications

Acceptance, Awareness, Attitude, and Practices toward Heart Transplantation: A Saudi Based Survey

Acceptance, Awareness, Attitude, and Practices toward Heart Transplantation: A Saudi Based Survey

Donor Characteristics and Outcomes of Pediatric Heart Transplantation in South Korea

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