2005
DOI: 10.2105/ajph.2004.044727
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The Weight of Scientific Evidence in Policy and Law

Abstract: The term "weight of evidence" (WOE) appears in regulatory rules and decisions. However, there has been little discussion about the meaning, variations of use, and epistemic significance of WOE for setting health and safety standards. This article gives an overview of the role of WOE in regulatory science, discusses alternative views about the methodology underlying the concept, and places WOE in the context of the Supreme Court's decision in Daubert v Merrell Dow Pharmaceuticals, Inc (1993). I argue that where… Show more

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Cited by 100 publications
(64 citation statements)
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“…The WoE method has been used extensively for mineral resource assessment and landslide susceptibility analysis (Bonham-Carter et al 1989, Carranza and Hale 2000, Porwal et al 2001, Lee et al 2002, Sterlacchini et al 2004. Following its use in the early 1990s to support US Superfund investigations, it has also become popular for performing risk assessments associated with ecology and environmental health (Krimsky 2005, Sanderson et al 2006, Irvine and Murphy 2009. Its application to the field of hydrogeology is more recent (e.g.…”
Section: Weights Of Evidence Methodsmentioning
confidence: 99%
“…The WoE method has been used extensively for mineral resource assessment and landslide susceptibility analysis (Bonham-Carter et al 1989, Carranza and Hale 2000, Porwal et al 2001, Lee et al 2002, Sterlacchini et al 2004. Following its use in the early 1990s to support US Superfund investigations, it has also become popular for performing risk assessments associated with ecology and environmental health (Krimsky 2005, Sanderson et al 2006, Irvine and Murphy 2009. Its application to the field of hydrogeology is more recent (e.g.…”
Section: Weights Of Evidence Methodsmentioning
confidence: 99%
“…For some indicator species, the trends are clear and different surveys indicate the same patterns (e.g., increases in Brown Pelican, declines for Mottled Duck), but for others, the evidence is conflicting. Thus, the data in this chapter can be examined with a weight of evidence approach, whereby the different types of data are examined in total to determine population status and trends in the Gulf (Burger 2003;Krimsky 2005;Laiolo 2010). Thus, if all (or almost all) data sets suggest that a given species is increasing, it is likely that it is.…”
Section: Patterns Of Population Changesmentioning
confidence: 99%
“…Generally, three objectives of the WOE approach are suggested for regulatory decision-making: i) provision of a "clear and transparent framework" for evaluation of the evidence in risk determination; ii) offer of a consistent and standardized approach to evaluating toxic substances submitted to regulatory agencies; and iii) help of identification of the discretionary assumptions in risk determinations from experts [12][13][14] . The GHS defines WOE as follows 2) : "All available information bearing on the determination of toxicity is considered together, including the results of valid in vitro tests, relevant animal data, and human experience such as epidemiological and clinical studies and well-documented case reports and observations.…”
Section: Evaluation Of Woe Among the Datamentioning
confidence: 99%
“…The issues of a WOE approach in GHS classification include: i) application of WOE depends on the expertise of experts; ii) there are no canonical frameworks for weighting scientific evidence; iii) a process methodology is low on transparency and high on subjectivity; iv) WOE is usually applied in the case where there is no conclusive single study in demonstrating a cause-effect relationship; v) WOE looks like a 'seat-of-the pants' qualitative assessment. Without an explanation of how evidence is "weighed" or "weighted", the WOE approach may be to be a "black box" of scientific judgment 13) . To keep transparency of expert reviews, the review should be objective and taken into consideration of evidence based toxicology 16) .…”
Section: Transparency and Objectivitymentioning
confidence: 99%