In order to realize the voltage conversion control of vacuum packaging machine seal, a design method of vacuum packaging machine seal transformer based on MCU control is proposed. The main function modules of the system are vacuum packaging machine seal physical index collection module, integrated control module, upper computer communication module, program control module, transformer load balance control module, human-computer interaction module, etc. In the intelligent auxiliary control system, the program cross compiling design of the sealing voltage conversion control of the vacuum packaging machine is carried out, the voltage conversion control is identified in the sealing process of the vacuum packaging machine, the characteristic quantity of the sealing transformer of the vacuum packaging machine is extracted, the human-computer interaction design of the sealing transformer of the vacuum packaging machine is carried out by using the visual operation and maintenance information management method, and the DSP is integrated The information transmission control of the sealed transformer of the vacuum packaging machine is realized. The simulation results show that the designed sealed transformer of vacuum packaging machine has good reliability and strong adaptive control ability, and improves the sealing pressure control ability of vacuum packaging machine.