“…The mechanism of this injury has been the subject of important controversy, since it bears on the type and potential efficacy of therapy. If, as Lewis, 22 Meryman 25 and many others believe, frostbite is essentially a thermal injury, the principal tissue damage has occurred by the time of rewarming and any or all subsequent measures will do little to alter the progression of pathologic events. If, however, vascular or other factors are of fundamental significance in the production of cell damage, there might be more hope for effective treatment.…”