The wrinkles soothing effect on the middle and lower face by intradermal injection of botulinum toxin type A

Chang, Shao Ping; Tsai, Hsiou Hsin; Chen, Wei Yu; Lee, William R.; Chen, Ping Ling; Tsai, Tsung Hsien

doi:10.1111/j.1365-4632.2008.03895.x

Cited by 54 publications

(84 citation statements)

References 28 publications

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“…43 Because botulinum toxin spreads in a three-dimensional manner after injection, the mechanism of action could be intramuscular or related to the overlying skin. Previous anecdotal reports of improvement in skin texture and turgor after intradermal toxin injection 44–46 have been attributed to intracutaneous fluid retention, by means of effects on acetylcholine receptors, which exist on keratinocytes, melanocytes, and cells of the sebaceous glands. 47 …”

Section: Evolving Concepts In Facial Agingmentioning

confidence: 99%

Global Aesthetics Consensus: Hyaluronic Acid Fillers and Botulinum Toxin Type A—Recommendations for Combined Treatment and Optimizing Outcomes in Diverse Patient Populations

Sundaram¹,

Liew²,

Signorini³

et al. 2016

Plastic &Amp; Reconstructive Surgery

120

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Section: Evolving Concepts In Facial Agingmentioning

confidence: 99%

Global Aesthetics Consensus: Hyaluronic Acid Fillers and Botulinum Toxin Type A—Recommendations for Combined Treatment and Optimizing Outcomes in Diverse Patient Populations

Sundaram¹,

Liew²,

Signorini³

et al. 2016

Plastic &Amp; Reconstructive Surgery

120

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show abstract

“…As the injected muscles relax, the surrounding tissue might relax as well. In addition, injection of BTX-A into the dermal–subdermal layer has been anecdotally reported to improve skin texture and turgor (11). Since the skin texture is better, the wrinkles will be improved and afterwards become shallower.…”

Section: Discussionmentioning

confidence: 99%

Facial Manifestations of Pachydermoperiostosis Treated with Botulinum Toxin Type-A: Report of 3 Cases

Wen

Li²,

Hamblin³

et al. 2017

Acta Derm Venerol

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“…41–43 The reported presence of intracutaneous acetylcholine receptors, eg, on sebaceous glands, 44 provides a possible mechanism for the observations of improved skin texture. 40 Recently, the reduction of sebum production in patients with oily skin following intradermal botulinum toxin type A injection was objectively demonstrated.…”

Section: Position Statementsmentioning

confidence: 99%

Aesthetic Applications of Botulinum Toxin A in Asians: An International, Multidisciplinary, Pan-Asian Consensus

Sundaram

Huang

Hsu³

et al. 2016

Plastic and Reconstructive Surgery - Global Open

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Background:Botulinum toxin type A remains the most popular nonsurgical aesthetic treatment worldwide. Previous consensus statements have focused on Caucasians and on Koreans as generally representative of Asians. However, indications and dosages vary among different ethnic groups. This publication reports the results of a multidisciplinary, pan-Asian consensus focusing on incobotulinumtoxinA.Methods:A consensus group of plastic surgeons and dermatologists from Asia, Europe, and the United States convened for a live meeting in Asia, followed by a questionnaire-based Delphi procedure. Treatment of Asians in both their native countries and countries of migration was discussed.Results:For most items, the group achieved a majority consensus. A number of treatment indications, strategies, and dosages were identified in Asians, which are distinct to those previously described for Caucasians due to differences in facial morphotypes, anatomy, and cultural expectations. The group also formulated position statements for intradermal botulinum toxin type A (“mesotoxin”), body shaping with the calves as a paradigm, and reduction of parotid glands. While Asians have previously been considered a homogeneous group for the purposes of aesthetic treatment, this publication considers regional variations. A new classification of Asian facial morphotypes is proposed to aid treatment planning and implementation.Conclusions:This is the first pan-Asian consensus for aesthetic use of botulinum toxin type A. Its unique objective is to optimize treatment safety and efficacy for patients of complete or part-Asian ancestry in all regions. The recommendations for incobotulinumtoxinA may be extended with care to other botulinum toxin formulations.

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The wrinkles soothing effect on the middle and lower face by intradermal injection of botulinum toxin type A

Abstract: Based on this pilot study, the face-lifting effect of intradermal injection with BTA was not conclusive. Interestingly, BTA showed moderate but significant wrinkles-soothing effect without obvious side effects on the lower face.

Cited by 54 publications

References 28 publications

Global Aesthetics Consensus: Hyaluronic Acid Fillers and Botulinum Toxin Type A—Recommendations for Combined Treatment and Optimizing Outcomes in Diverse Patient Populations

Global Aesthetics Consensus: Hyaluronic Acid Fillers and Botulinum Toxin Type A—Recommendations for Combined Treatment and Optimizing Outcomes in Diverse Patient Populations

Facial Manifestations of Pachydermoperiostosis Treated with Botulinum Toxin Type-A: Report of 3 Cases

Aesthetic Applications of Botulinum Toxin A in Asians: An International, Multidisciplinary, Pan-Asian Consensus

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