The Yield of Capsule Endoscopy in Patients with Abdominal Pain or Diarrhea

Fry, Lucía C.; Carey, Elizabeth J.; Shiff, Arthur D.; Heigh, Russell I.; Sharma, Virender K.; Post, Janice; Hentz, Joseph G.; Fleischer, DE; Leighton, Jonathan A.

doi:10.1055/s-2006-925340

Cited by 75 publications

(48 citation statements)

References 19 publications

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“…Suspicion of Crohn’s disease was previously left to the discretion of the treating physician and usually was considered when a patient had either abdominal pain or persistent diarrhea. Yields of capsule endoscopy are low when performed in patients with abdominal pain alone and in patients with abdominal pain and diarrhea alone [6,7]. When other criteria are added this yield increases.…”

Section: Suspected Crohn’s Diseasementioning

confidence: 99%

Capsule Endoscopy and Crohn’s Disease

Hartmann

2011

Dig Dis

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Capsule endoscopy has been shown to detect small bowel inflammatory changes better than any other imaging modality. Selection criteria have been optimized to increase the yield of capsule endoscopy in patients suspected of having Crohn’s disease. Capsule endoscopy allows for earlier diagnosis of Crohn’s disease of the small bowel and improved diagnosis of colitis in patients where it is unclear if they suffer from Crohn’s or ulcerative colitis. A test capsule is available to assess for small bowel strictures and thus avoid capsule retention. It is envisioned that the manner in which we treat Crohn’s disease in the future will change, based on earlier diagnosis and treatment aimed at mucosal healing rather than symptom improvement.

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Section: Suspected Crohn’s Diseasementioning

confidence: 99%

Capsule Endoscopy and Crohn’s Disease

Hartmann

2011

Dig Dis

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“…In a prospective blinded study, VCE had superior diagnostic accuracy when compared to MRE and CTE in Crohn's disease [77]. In patients with abdominal pain and/or diarrhea, without associated findings of weight loss/growth failure, elevated inflammatory makers or abnormal imaging studies, the yield of capsule endoscopy is low [78,79]. Because VCE has a high risk of capsule retention in Crohn's disease, CTE or MRE is useful to detect small bowel wall thickening or stricture before considering VCE (Fig.…”

Section: Ulcerating Diseasementioning

confidence: 97%

Advances in Small Bowel Imaging

Tennyson

Semrad

2011

Curr Gastroenterol Rep

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The small intestine has been difficult to examine by traditional endoscopic and radiologic techniques. Within the past 10 years, advances have led to an explosion of technologies that facilitate examination of the entire small intestine. Wireless video capsule endoscopy, deep enteroscopy using balloon-assisted or spiral techniques, computer tomography (CT) and magnetic resonance (MR) enterography have facilitated the diagnosis, monitoring, and management of patients with small intestinal diseases. These technologies are complementary, each with its advantages and limitations. Capsule endoscopy provides a detailed view of the mucosal surface and has excellent patient acceptance, but does not allow therapeutics. Deep enteroscopy allows careful inspection of the mucosa and therapeutics, but is time consuming and invasive. Enterography (CT or MR) allows examination of the small bowel wall and surrounding structures. The initial best test for detecting small intestinal disease depends on clinical presentation and an astute differential diagnosis.

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“…Occult GI bleeding accounts for up to two-thirds of SBCE studies performed [12]. It was shown that 20-38 % of patients with normal upper and lower endoscopy have significant intestinal lesions [13,14] (Fig.…”

Section: Occult Gi Bleedingmentioning

confidence: 99%