Horndeski gravity is the most general scalar tensor theory, with a single scalar field, leading to second-order field equations and after the GW170817 it has been severely constrained. Since this theory is very important in modified gravity, it is then worth studying possible similar theories starting from other frameworks. In this paper, we study the analog of Horndeski's theory in the Teleparallel Gravity framework where gravity is mediated through torsion instead of curvature. We show that, even though, many terms are the same as in the curvature case, we have much richer phenomenology in the teleparallel setting because of the nature of the torsion tensor. Moreover, teleparallel Horndeski contains the standard Horndeski gravity as a subcase and also contains many modified Teleparallel theories considered in the past, such as f (T ) gravity or teleparallel dark energy. Thus, due to the appearance of a new term in the Lagrangian, this theory can explain dark energy without a cosmological constant, may describe a crossing of the phantom barrier, explain inflation and also solve the tension for H0, making it a good candidate for a correct modified theory of gravity.