Abstract. Let g be a finite dimensional simple Lie algebra over and algebraically closed field K of characteristic 0. Let g Z be a Chevalley Z-form of g and g k = g Z ⊗ Z k, where k is the algebraic closure of F p . Let G k be a simple, simply connected algebraic k-group with Lie(G k ) = g k . In this paper, we apply recent results of Rudolf Tange on the fraction field of the centre of the universal enveloping algebra U (g k ) to show that if the Gelfand-Kirillov conjecture (from 1966) holds for g, then for all p ≫ 0 the function field k(g k ) on the dual space g k is purely transcendental over its subfield k(g k ) G k . Very recently, it was proved by Colliot-Thélène-Kunyavskiȋ-Popov-Reichstein that the function field K(g) is not purely transcendental over its subfield K(g) g provided that g is of type B n , n ≥ 3, D n , n ≥ 4, E 6 , E 7 , E 8 or F 4 . We prove a modular version of this result (valid for p ≫ 0) and use it to show that, in characteristic 0, the Gelfand-Kirilov conjecture fails for the simple Lie algebras of the above types. In other words, if g of type B n , n ≥ 3, D n , n ≥ 4, E 6 , E 7 , E 8 or F 4 , then the Lie field of g is more complicated than expected.