A modified integral counting method (MICM) with various quenched samples (MICM-VQ) has been investigated for its applicability for different scintillators using b emitters, 14 C and 35 S. To assess the influence of scintillators, three sets of 14 C quenched standards and two 35 S cocktail series were prepared. Two sets of 14 C quenched standards were used for the toluene-compatible scintillator, the other for the Ultima Gold™ scintillator. Sulfur-35 cocktail series were prepared with either Ecoscint™ XR or Ultima Gold™ AB. The radioactivity of these samples was determined using the MICM-VQ, with the results conforming to assayed values. Hence the MICM-VQ can assay the radioactivity of sample cocktails with various scintillators and requires no standard sample.