1996
DOI: 10.1007/bf02190278
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The Zurich Study: XXII

Abstract: A representative cohort of Swiss adults recruited at age 20 years and interviewed at ages 23, 28 and 30 years was studied regarding the symptomatology, prevalence and longitudinal course of functional gastrointestinal symptoms and their association with psychiatric syndromes. A functional gastrointestinal complaint was identified if a proband reported symptoms at least eight times in the past year or for a duration of at least 2 weeks without medical explanation and with a moderate degree of distress. Of the p… Show more

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Cited by 42 publications
(12 citation statements)
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“…No firm conclusions can thus be drawn as to their reliability, validity and prognostic value. The findings of this study are, however, consistent with the available literature on FGID as to the high comorbidity of the mood and anxiety disorders [13, 14, 15, 16, 17], the presence of other, non-gastrointestinal-related, medically unexplained symptoms [49, 50, 51]and the low pain threshold in bodily sites beyond the symptom-related region of the gastrointestinal tract [52]. They are also consistent with the growing awareness of the importance of subclinical affective symptomatology [53, 54], particularly in the medical setting [22].…”
Section: Discussionsupporting
confidence: 79%
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“…No firm conclusions can thus be drawn as to their reliability, validity and prognostic value. The findings of this study are, however, consistent with the available literature on FGID as to the high comorbidity of the mood and anxiety disorders [13, 14, 15, 16, 17], the presence of other, non-gastrointestinal-related, medically unexplained symptoms [49, 50, 51]and the low pain threshold in bodily sites beyond the symptom-related region of the gastrointestinal tract [52]. They are also consistent with the growing awareness of the importance of subclinical affective symptomatology [53, 54], particularly in the medical setting [22].…”
Section: Discussionsupporting
confidence: 79%
“…These patients have been found in fact to present with considerable psychological and psychiatric problems in a number of investigations [13, 14, 15, 16, 17]. The preliminary results on 70 of these patients have already been reported [18].…”
Section: Introductionmentioning
confidence: 83%
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“…The psychiatric comorbidity in FGIDs is a challenging diagnostic task for both gastroenterologists and psychiatrists. Although a high prevalence of psychopathology among patients with FGIDs has been demonstrated in several studies [7, 28, 29, 30], and the pathophysiology of FGIDs is conceptually close to the process of somatization [3], the exclusion rule of the DSM-IV may constitute an important limitation to the recognition of comorbidity, and produce a risk for underdiagnosing FGIDs in psychiatric settings. According to the DSM-IV, somatoform disorders are not diagnosed if the medically unexplained somatic symptoms are accounted for better by another mental disorder, particularly a mood or anxiety disorder.…”
Section: Discussionmentioning
confidence: 99%
“…Klonoff et al [13] already provided a description of fear of nausea which was closely related to current definitions of fear of vomiting, in line with the idea that nausea may be particularly relevant to the etiological processes in SPOV. Further, nausea correlates with anxiety [14] and gastrointestinal complaints appear to be significantly associated with a number of anxiety disorders [15]. In addition, while nausea or gastrointestinal symptoms are acknowledged as secondary symptoms in social phobia [15,16] they could play a more crucial and central role in the development of SPOV.…”
Section: Introductionmentioning
confidence: 99%