Thenar hypoplasia with associated radiologic abnormalities

Cavanagh, N. P. C.; Yates, D A H; Sutcliffe, Jonathan

doi:10.1002/mus.880020604

Cited by 17 publications

(12 citation statements)

References 9 publications

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“…1,10 Other published and possible conditions that might provoke carpal tunnel syndrome in children are listed in Table 3. 2,[9][10][11][12][13][14] In carpal tunnel syndrome secondary to mucopolysaccharidoses and mucolipidoses, clinical signs typical of adult carpal tunnel syndrome are rarely seen, and difficulty with fine motor tasks is the most frequent finding (as in our case 6). In such cases, carpal tunnel syndrome probably develops because of a combination of factors, such as excessive lysosomal storage in the connective tissue of the flexor retinaculum and anatomic changes caused by bone dysplasia.…”

Section: Discussionmentioning

confidence: 66%

Carpal Tunnel Syndrome in Children

et al. 2013

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Carpal tunnel syndrome rarely occurs in children. We retrospectively analyzed clinical data of 11 patients aged 5-17 diagnosed with carpal tunnel syndrome at a single pediatric neuromuscular center. Nerve conduction studies were performed according to the American Association of Electrodiagnostic Medicine recommendations. Additional imaging tests of the wrist were performed in 10 patients. In our group of 11 children, carpal tunnel syndrome was idiopathic in only 1 case. In the remaining subjects, it was secondary to congenital bone anomaly (6), hypothyroidism (2), or myopathic contractures (1). In 1 case, metabolic workup revealed an underlying mucopolysaccharidosis. Our results confirm that idiopathic carpal tunnel syndrome is rare in children. Hand clumsiness and thenar hypoplasia rather than sensory complaints are the presenting symptoms. Whenever carpal tunnel syndrome is diagnosed in a child, a thorough differential diagnosis should be made because of the secondary nature of this disease in most pediatric patients.

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Section: Discussionmentioning

confidence: 66%

Carpal Tunnel Syndrome in Children

et al. 2013

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“…CS is an uncommon disorder of the upper extremities which presents with unilateral or bilateral hypoplasia of the Thenar eminence. The clinical, radiological and electrodiagnostic features were first described by Cavanagh et al [1]. All five patients studied had either unilateral or bilateral underdevelopment of the muscles of the thenar eminence, with normal sensation in the median nerve distribution.…”

Section: Introductionmentioning

confidence: 86%

“…While both CTS and CS may have low-amplitude CMAPs, electrophysiologic testing in CS thus far has shown normal sensory potentials [24]. In CS, the median sensory supply to the hand is not affected, with the skin over the thenar eminence being supplied by the palmar cutaneous branch, and the volar thumb, index finger, middle finger and lateral half of the ring finger supplied by the digital cutaneous branches of the median nerve [1,25,26]. Other differences include normal conduction velocity, normal distal latency, and normal insertional activity in isolated CS, all of which may be abnormal in CTS.…”

Section: Diagnosis Of Cts In Patients With Csmentioning

confidence: 99%

Diagnosing Carpal Tunnel Syndrome in Cavanagh Syndrome: A Literature Review and Proposed Electro Physiologic Protocol

Kumbhare¹,

Mian²,

Singh³

et al. 2017

Pain Manage Med

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Objective: To summarize the literature on the electrophysiology of Cavanagh Syndrome (CS), to present a clinical application and to propose an updated electrophysiologic protocol. Methods:A systematic literature search for CS was carried out and a clinical application is presented.Results: CS is characterized by congenital thenar hypoplasia and can be associated with other regional muscular and vascular anomalies. The main electrophysiologic abnormality in patients with CS is a reduced amplitude median compound muscle action potential (CMAP) to the thenar eminence, which is also seen in CTS. Radiographic, and electrodiagnostic findings of a patient with co-morbid CS and CTS is presented. Evaluating the median CMAP to the first lumbrical may assist with the diagnosis of CTS in patients with CS. Conclusions:As CTS and CS can present with thenar atrophy and low amplitude CMAPs, electromyographers should be aware of the clinical and radiographic characteristics of CS and consider electrophysiologic evaluation of the first lumbrical.

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“…Most children with CTS do not have typical symptoms, and progressive clumsiness of the hand and thenar atrophy may be a presenting feature ( Van Meir and De Smet, 2003 ) . The prominent thenar wasting in a child can also represent a developmental anomaly of the hand ( Cavanagh et al, 1979 ) ; hence, a careful diagnostic workup is necessary before a decision of surgical treatment of CTS in children.…”

mentioning

confidence: 99%

“…Congenital thenar hypoplasia accompanying anomalies of the metacarpal bones is known as Cavanagh syndrome ( Cavanagh et al, 1979 ) . The electrophysiological studies in Cavanagh syndrome patients reveal absent or low‐amplitude CMAPs recorded from the thenar muscles and normal median sensory responses, excluding the diagnosis of CTS.…”

mentioning

confidence: 99%