THEORETICAL AND EXPERIMENTAL INVESTIGATION OF PYRIDYL-THIOUREA DERIVATIVES AS IONOPHORES FOR Cu(II) ION DETECTION

Abstract

Copper (II) ion chemical sensors based on pyridine-thiourea derivatives; N-pyridyl-N'-(biphenyl-4-carbonyl)thiourea (L1), and N-pyridyl-N'-(3,5-dimethyoxybenzoyl)thiourea (L2) were synthesised, characterised, and studied as ionophores in the form of thin-films PVC membranes. The ionophores exhibited good responses towards copper (II) ion over the concentration range of 2 x 10 -4 to 10 x 10 -4 M with a limit of detection 1.34 x 10 -5 to 1.48 x 10 -5 M. The proposed sensors L1 and L2 revealed good performance in term of reproducibility and regeneration of the ionophores with low relative standard deviation (RSD) values 4.17 % and 2.74 % respectively. Besides, quantum chemical calculation performed using Gaussian 09 program indicated the oxygen (O) atom from carbonyl moiety (C=O) was the most favourite reactive site and mainly responsible for ionophore-Cu(II) interaction. The obtained data revealed pyridine-thiourea derivatives offered great potential as ionophore for the detection of Cu (II) ion.

Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3-(substituted) thioureas

“…The sensors performed well towards different Cu 2? ion concentrations and are being used as striking ionophores [113].…”

Construction of an optical sensor for copper determination in environmental, food, and biological samples based on the covalently immobilized 2-(2-benzothiazolylazo)-3-hydroxyphenol in agarose

“…There are several Cu 2+ ion detection methods reported in the literature based on reectance, 62 uorescence, 63,70 transducers, optical absorption, 23,[64][65][66][67][68][69][71][72][73][74] and the use of different immobilization substrates. A comparison of the sensing performance of the Cu 2+ ion optode developed in this work with similar methods from other literature reports is summarized in Table 1 with regard to dynamic linear response range and limit of detection.…”

A Potentiometric Sensor for the Determination of Pb(II) Ions in Different Environmental Samples

“…[30,31] Molecules containing multiple donor atoms such as sulfur, oxygen and nitrogen in their structure are more preferred as ionophores in the preparation of chemical sensors, as these atoms provide the ability to complex with metals quite easily. [32] In this study, a novel hydrazinecarbothiomaide derivative molecule (Figure 1) was synthesized and its ionophore properties were investigated. The synthesized novel molecule exhibited high selectivity towards Pb(II) ions and its potentiometric performance properties were tested.…”