The plasma window is a windowless vacuum sealing device that utilizes a cascade arc discharge to isolate regions with different pressures. It was proposed as an alternative to the traditional windowless sealing technology of differential pumping, which greatly improves the sealing efficiency and has been successfully applied in electron beam welding. The discharge channel of the existing plasma window is a small circular hole, referred to as a zero-dimensional plasma window, which has limited applications to its dimensions. In this study, we suggested a one-dimensional (1D) plasma window with a slit discharge channel (cross section: 3 × 35 mm2, length: 60 mm). An arc discharge is realized with the support of an 80 A DC power supply, which can maintain a pressure drop of more than 10 times between the high-pressure and low-pressure ends of the plasma window. A COMSOL-based magneto-hydrodynamic model of the plasma window was established, and simulations were in good agreement with the experimental results. The pressure drop in the plasma window caused by argon plasma has also been theoretically analyzed and discussed. The feasibility of a 1D plasma window to achieve vacuum isolation was verified theoretically, numerically, and experimentally.